Twenty-five cases of neuroendocrine carcinoma of the thymus associated with Cushing's syndrome have been reported since 1972.1 We report two new cases of thymic carcinoid, one of which presented with Cushing's disease. These patients were successfully treated and were asymptomatic at the time of first follow-up.
Get full access to this article
View all access options for this article.
References
1.
EconomopoulosGCLewisJWJrLeeMWSilvermanNA. Carcinoid tumors of the thymus. Ann Thorac Surg1990; 50:58–61.
2.
DuhQYHybargerCPGeistRGamsuGGoodmanPCGoodingGA. Carcinoids associated with multiple endocrine neoplasia syndromes. Am J Surg1987; 154:142–8.
3.
de MontprevilleVTMacchiariniPDulmetE. Thymic neuroendocrine carcinoma (carcinoid): A clinicopathologic study of fourteen cases. J Thorac Cardiovasc Surg1996; 111:134–41.
4.
de PerrotMSpiliopoulosAFischerSTotschMKeshavjeeS. Neuroendocrine carcinoma (carcinoid) of the thymus associated with Cushing's syndrome. Ann Thorac Surg2002; 73:675–81.
5.
de HerderWWUitterlindenPPietermanHTangheHLKwekkeboomDJPolsHA. Pituitary tumour localization in patients with Cushing's disease by magnetic resonance imaging. Is there a place for petrosal sinus sampling?Clin Endocrinol (Oxf)1994; 40:87–92.
6.
RosaiJHigaE. Mediastinal endocrine neoplasm, of probable thymic origin, related to carcinoid tumor. Clinicopathologic study of 8 cases. Cancer1972; 29:1061–74.
7.
ImuraHMatsukuraSYamamotoHHironosukeHHirataYNakaiY. Studies on ectopic ACTH-producing tumors. II. Clinical and biochemical features of 30 cases. Cancer1975; 35:1430–7.
8.
MillerDLDoppmanJL. Petrosal sinus sampling: Technique and rationale. Radiology1991; 178:37–47.