Invasive pulmonary aspergillosis is a serious complication in immunocompromised patients. In those unresponsive to pharmacological treatment, or when drug toxicity is excessive, surgery may resolve the condition. A 48-year-old woman with invasive pulmonary aspergillosis after renal transplantation underwent resection of the right upper lobe and the apical segment of the inferior lobe, followed by complete recovery.
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References
1.
LymanCAWalshTJ. Phagocytosis of medically important yeasts by polymorphonuclear leukocytes. Infect Immun1994; 62: 1489–93.
2.
ReichenbergerFHabichtJMGratwohlATammM. Diagnosis and treatment of invasive pulmonary aspergillosis in neutropenic patients. Eur Respir J2002; 19: 743–55.
3.
WeilandDFergusonRMPetersonPKSnoverDCSimmonsRLNajarianJS. Aspergillosis in 25 renal transplant patients. Epidemiology, clinical presentation, diagnosis, and management. Ann Surg1983; 198: 622–9.
4.
WingardJRBealsSUSantosGWMerzWGSaralR. Aspergillus infections in bone marrow transplant recipients. Bone Marrow Transplant1987; 2: 175–81.
5.
KusneSTorre-CisnerosJManezRIrishWMartinMFungJFactors associated with invasive lung aspergillosis and the significance of positive Aspergillus culture after liver transplantation. J Infect Dis1992; 166: 1379–83.
6.
ReichenbergerFHabichtJKaimADalquenPBernetFSchlapferRLung resection for invasive pulmonary aspergillosis in neutropenic patients with hematologic disease. Am J Respir Crit Care Med1998; 158: 885–90.
7.
StevensDAKanVLJudsonMAMorrisonVADummerSDenningDWPractice guidelines for disease caused by Aspergillus. Infectious Diseases Society of America. Clin Infect Dis2000; 30: 696–709.
8.
HabichtJMReichenbergerFGratwohlAZerkowskiHRTammM. Surgical aspects of resection for suspected invasive pulmonary fungal infection in neutropenic patients. Ann Thorac Surg1999; 68: 321–5.
