A 57-year-old Caucasian woman presented with nonproductive cough. Computed tomography revealed a peripheral solid mass in the upper lobe of the left lung. She underwent thoracotomy and upper lobectomy. Histology of the excised tumor demonstrated lymphoepithelioma-like carcinoma of the lung, with no associated Epstein-Barr virus activity. Being a rare entity and mostly seen in Asians, very few cases have been described previously.
Get full access to this article
View all access options for this article.
References
1.
FranklinWA. Diagnosis of lung cancer: pathology of invasive and preinvasive neoplasia. Chest2000;117: S80–9.
2.
ButlerAEColbyTVWeissLLombardC. Lymphoepithelioma-like carcinoma of the lung. Am J Surg Pathol1989;13: 632–9.
3.
FrankMWShieldsTWJoobAWKiesMSSturgisCDYeldandiALymphoepithelioma-like carcinoma of the lung. Ann Thorac Surg1997;64: 1162–4.
CurcioLDCohenJSGrannisFWJrPazIBChilcoteRWeissLM. Primary lymphoepithelioma-like carcinoma of the lung in a child. Report of an Epstein-Barr virus-related neoplasm. Chest1997;111: 250–1.
6.
ChenFFYanJJLaiWWJinYTSuIJ. Epstein-Barr virus-associated nonsmall cell lung carcinoma: undifferentiated “lymphoepithelioma-like” carcinoma as a distinct entity with better prognosis. Cancer1998;82: 2334–42.
7.
ChanATTeoPMLamKCChanWYChowJHYimAPMultimodality treatment of primary lymphoepithelioma-like carcinoma of the lung. Cancer1998;83: 925–9.
8.
HoJCLamWKOoiGCLamBTsangKW. Chemoradiotherapy for advanced lymphoepitheliomalike carcinoma of the lung. Respir Med2000;94: 943–7.