The occurrence of several cases of atrial septal defect in the same family is rare. A family in which the father and his two daughters presented with atrial septal defect associated with atrioventricular conduction abnormalities is described.
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References
1.
BassonCTSolomonSDWeismannBMacraCAPoznanskiAKPrietoFGenetic heterogeneity of heart-hand syndromes. Circulation1995;91: 1326–9.
2.
Newbury-EcobRALeanageRRaeburnJAYoungID. Holt-Oram syndrome: a clinical genetic study. J Med Genet1996;33: 300–7.
3.
ThomasDLascaultGCailleBDrobinskiGHubermanJPShqueirAFamilial forms of interauricular communication of the ostium secundum type. Arch Mal Coeur Vaiss1985;78: 1205–9.
4.
LynchHTBachenbergKHarrisREBeckerW. Hereditary atrial septal defect. Update of a large kindred. Am J Dis Child1978;132: 600–4.
5.
MegarbaneAStephanEKassabRAshoushRSalemNBouvagnetPAutosomal dominant secundum atrial septal defect with various cardiac and noncardiac defects: a new midline disorder. Am J Med Genet1999;83: 193–200.
6.
WeiklARottHDLangE. Autosomal dominant hereditary atrial septal defect with heart conduction defects and mitral valve insufficiency. Z Kardiol1976;65: 606–15.
7.
SchottJJBensonDWBassonCTPeaseWSilberbachGMMoakJPCongenital heart disease caused by mutations in the transcription factor NKX2-5. Science1998;281: 108–11.
