Forty-two symptomatic patients underwent both electron-beam computed tomo-graphic calcium scoring and coronary angiography. Correlation between coronary artery calcium score and angiographic coronary disease showed a high specificity (90%) but low sensitivity (50%). The low negative predictive value of 36% suggests that electron-beam computed tomography is not useful in symptomatic patients.
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References
1.
AgatstonASJanowitzWRHildnerFJZusmerNRViamonteMDetranoR. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol1990;15: 827–32.
2.
SimonsDBSchwartzRSEdwardsWDSheedyPFBreenJFRumbergerJA. Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: A quantitative pathologic comparison study. J Am Coll Cardiol1992;20: 1118–26.
3.
RumbergerJASimonsDBFitzpatrickLASheedyPFSchwartzRS. Coronary artery calcium area by electronbeam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation1995;92: 2157–62.
4.
AradYSpadaroLAGoodmanKLledo-PerezAShermanSLernerG. Predictive value of electron beam CT of the coronary arteries: 19-month follow-up of 1173 asymptomatic subjects undergoing coronary artery calcification screening by electron beam tomography. Circulation1996;93: 1951–3.
5.
ShieldsJPMielkeCHJrWatsonP. Inter-rater reliability of electron beam computed tomography to detect coronary artery calcification. Am J Card Imaging1996;10: 91–6.
6.
RumbergerJASchwartzRSSimonsDBSheedyPFEdwardsWDFitzpatrickLA. Relation of coronary calcium determined by electron beam computed tomography and lumen narrowing determined by autopsy. Am J Cardiol1994;74: 1169–73.
7.
BreenJBSheedyPFSchwartzRSStansonAWKaufmannRBMollPP. Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease. Radiology1992;185: 435–9.
8.
MautnerSLMautnerGCFroehlichJFeuersyeinIMProschanMARobertsWC. Coronary artery disease: Prediction with in vitro electron beam CT. Radiology1994;192: 625–30.
9.
FallavollitaJABrodyASBunnellILKumarKCantyJM. Fast computed tomography detection of coronary calcification in the diagnosis of coronary artery disease: Comparisons with angiography in patients < 50 years old. Circulation1994;89: 285–90.
10.
BielakLFKaufmannRBMollPPMcColloughCHSchwartzRSSheedyPF. Small lesions in the heart identified at electron beam CT: Calcification or noise. Radiology1994;192: 631–6.
11.
DevriesSWolfkielCFusmanBBakdashHAhmedALevyP. Influence of age and gender on the presence of coronary calcium detected by ultrafast computed tomography. J Am Coll Cardiol1995;25: 76–82.
12.
RumbergerJASheedyPFBreenJFSchwartzRS. Coronary calcium, as determined by electron beam com-puted tomography, and coronary disease on arteriogram: Effect of patient's sex on diagnosis. Circulation1995;91: 1363–7.
13.
BudhoffMJGeorgiouDBrodyAAgatstonASKennedyJWolfkielC. Ultrafast computed tomography as a diagnostic modality in the detection of coronary artery disease: A multicenter study. Circulation1996;93: 898–904.
14.
AradYSpadaroLAGoodmanKLledoAShermanSGuerciAD. 3.6 years follow-up of 1136 asymptomatic adults undergoing electron beam CT (EBCT) of the coronary arteries [abstract]. J Am Coll Cardiol1998;31 (Suppl A): 210A.
15.
RumbergerJA. Arterial calcification, electron beam computed tomography, and early diagnosis of coronary atherosclerosis. ACC Educational Highlights. Bethesda: American College of Cardiology, 1998;4: 19–22.
16.
AchenbachSMoshageWRopersDNossenJDanielWG. Value of electron-beam computed tomography for the noninvasive detection of high-grade coronary-artery stenoses and occlusions. N Engl J Med1998;339: 1964–71.
17.
RensingBJBongaertsAvan GeunsRJvan OoijenPOudkerkMde FeyterPJ. Intravenous coronary angio-graphy by electron beam computed tomography — a clinical evaluation. Circulation1998;98: 2509–12.
