Tonotopic organization is a major feature of central auditory structures. The tritiated 2-deoxyglucose metabolic marking technique is demonstrated to be useful for visualizing isofrequency contours in the rat inferior colliculus. Following pure-tone stimulation, the central nucleus of the inferior colliculus shows discrete, prominent banding patterns and a well-organized tonotopic arrangement.
Get full access to this article
View all access options for this article.
References
1.
GeniecPMorestDK: The neuronal architecture of the human posterior colliculus. Acta Otolaryngol Suppl1971; 295: 1–33.
2.
RockelAJJonesEG: The neuronal organization of the inferior colliculus of the adult cat: I. The central nucleus. J Comp Neurol1973; 147: 11–60.
3.
GoldbergJMMooreRY: Ascending projections of the lateral lemniscus in the cat and monkey. J Comp Neurol1967; 129: 143–146.
4.
BeyerlBD: Afferent projections to the central nucleus of the inferior colliculus in the rat. Brain Res1978; 145: 209–223.
5.
AdamsJC: Ascending projections to the inferior colliculus. J Comp Neurol1979; 183: 519–538.
6.
RothGLAitkinLMAndersenRA: Some features of the spatial organization of the central nucleus of the inferior colliculus of the cat. J Comp Neurol1978; 182: 661–680.
7.
SempleMNAitkinLM: Representation of sound frequency and laterality by units in central nucleus of cat inferior colliculus. J Neurophysiol1979; 42: 1626–1639.
8.
SokoloffL: Relation between physiological function and energy metabolism in the central nervous system. J Neurochem1977; 29: 13–26.
9.
HungerbühlerJPSaundersJCGreenbergJ: Functional neuroanatomy of the auditory cortex studied with 2-[14C]deoxyglucose. Exp Neurol1981; 71: 104–121.
10.
WebsterWRServiereJBatiniC: Autoradiographic demonstration with 2-[14C]deoxyglucose of frequency selectivity in the auditory system of cats under conditions of functional activity. Neurosci Lett1978; 10: 43–48.
11.
RyanAFWoolfNKSharpFR: Tonotopic organization in the central auditory pathway of the mongolian gerbil: A 2-deoxyglucose study. J Comp Neurol1982; 207: 369–380.
12.
GoocheeCRasbandWSokoloffL: Computerized densitometry and color coding of [14C]deoxyglucose autoradiographs. Ann Neurol1980; 7: 359–370.
13.
CloptonBMWinfieldJA: Tonotopic organization in the inferior colliculus of the rat. Brain Res1973; 56: 355–358.
14.
SykaJDrugaRPopelarJ: Functional organization of the inferior colliculus, inSykaJAitkinL (eds): Neuronal Mechanisms of Hearing. New York, Plenum Press,1981, pp 137–153.
15.
AitkinLMDickhausHSchultW: External nucleus of inferior colliculus: Auditory and spinal somatosensory efferents and their interactions. J Neurophysiol1978; 41: 837–847.
