Pituitary gland tumors are most commonly adenomas of the glandular tissue. They are benign, slow-growing tumors confined to the pituitary fossa region. Pituitary tumors that become aggressive, involving contiguous bony structures and brain, as well as metastasizing out of the confines of the skull, are referred to as pituitary carcinomas. This case of pituitary carcinoma is the first reported in the literature occurring as a middle ear tumor. The literature documents many cases of pituitary carcinoma. The history and medical treatment of this case are presented.
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