A patient in whom multiple, familial, catecholamine-secreting head and neck paragangliomas and retroperitoneal pheochromocytomas were identified is reported. There were at least nine primary and possibly five recurrent neoplasms, the most reported in a single patient.
In patients with family history of pheochromocytoma or paraganglioma or with multiple tumors, careful laboratory and angiographic studies are indicated to discover additional lesions.
Get full access to this article
View all access options for this article.
References
1.
AlfordBR, GuilfordFR: A comprehensive study of tumors of the glomus jugulare. Laryngoscope72: 765–787, 1962.
2.
SpectorGJ, CiralskyR, MaiselRH: IV. Multiple glomus tumors in the head and neck. Laryngoscope85: 1066–1075, 1975.
3.
ChedidA, JaoW: Hereditary tumors of the carotid bodies and chronic obstructive pulmonary disease. Cancer33: 1635–1641, 1974.
4.
ZacksSI: Chemodectomas occurring concurrently in the neck (carotid body), temporal bone (glomus jugulare), and retroperitoneum. Am J Pathol34: 293–309, 1958.
5.
ReichNE, AdlerLM, DuchesneauPM: Norepinephrine- and epinephrine-secreting paraganglioma of the jugular glomus. Neuroradiology8: 263–265, 1975.
6.
MatsuguchiH, TsuneyoshiM, TakeshitaA: Nonadrenalin-secreting glomus jugulare tumor with cyclic change of blood pressure. Arch Intern Med135: 1110–1113, 1975.
7.
ColdwaterKB, DirksKR: Chemodectoma of the glomus intravagale. Surgery40: 1069–1080, 1956.
