Abstract
Objectives:
Investigate the efficacy of preemptive montelukast, which is leukotreine receptor blocker for pediatric posttonsillectomy pain management. This is the first time montelucast has been used in posttonsillectomy pain control.
Methods:
A total of 60 children, aged 5 to 15 years, American Society of Anesthesiologist (ASA) class I-II, scheduled for elective tonsillectomy were enrolled in this double-blinded and controlled study from April of 2013 until January of 2014. The patients were randomized into 2 groups: Montelukast group (Group M, n:30) and control group (Group C, n:30). Group M received 5 mg oral montelukast tablet and Group C received placebo at 24:00 pm the night before surgery. The posttonsillectomy pain was evaluated with Wong-Baker Face Scale during the 24 hours after surgery. Postoperative complications were recorded. The data were analyzed using the Student t test. Data were presented as a mean + SD, and differences were considered significant at P < .05.
Results:
There were statistically significant differences between Wong-Baker Face Scale scores of the Group C and Group M (P < .05). The first time, analgesic requirement was higher in group C than in group M (P < .05).There was no significant difference in demographic parameters and postoperative complications (P > .05 for both).
Conclusions:
Preemptive montelukast usage is more effective than the control group in posttonsillectomy pain relief.
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