Abstract
Program Description:
The next breakthrough in surgery will be intraoperative visualization of key normal structures and diseased tissue in real time using biological targeting compounds. Agents for visualizing blood flow are currently available to evaluate flap perfusion or vessel dynamics and sentinel node detection. Both antibody-based agents and small molecules with high-affinity target binding linked to fluorophores can be detected with high sensitivity using currently available cameras. Agents are being developed for imaging nerves. There are active clinical trials to image cancer cells to ensure complete resection. This miniseminar will provide an overview of agents that are currently available and in development.
Educational Objectives:
(1) Describe the utility of optical imaging in head and neck surgery. (2) Implement currently available optical imaging agents in surgical practice. (3) Analyze validity of new agents and instruments that will be coming to the market for surgical optical imaging.
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