Abstract
Program Description:
Detection and treatment of precancerous lesions is a challenge given the widespread nature of these lesions. Advances in optical visualization using the world’s smallest microscope, availability of commercial products evaluating fluorescent targeting of abnormal tissue and molecular biology will play an important role in determining when to initiate treatment. Clinical trials with promising targeted agents and nutraceuticals, a billion dollar industry, will be discussed. With the emerging epidemic of HPV tumors early detection and prevention will be key in counseling patients and their families. Screening salivary rinses and serum for markers of early detection or persistent disease will be discussed.
Educational Objectives:
1) Apply novel approaches for HPV detection and prevention of oropharyngeal cancer. 2) Recognize intra-operative detection and treatment of premalignant lesions using the world’s smallest microscope, novel fluorescent agents, and laser treatment. 3) Describe chemoprevention of head and neck squamous cell carcinoma with special emphasis on clinical trials with targeted agents and nutraceuticals.
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