Abstract
Objective: To determine the incidence of laryngopharyngeal symptoms and signs in gastroesophageal reflux disease and to assess the response of these symptoms and signs to antireflux therapy.
Method: Thirty patients were selected for this 2-year prosepective randomized case control study based on the inclusion and exclusion criteria. A complete history, videolaryngoscopy, UGI endoscopy with biopsy, and 24-hour pH monitoring were performed. Ten healthy volunteers without any laryngopharyngeal symptoms or symptoms of GERD were used as controls.
Results: In this 2-year prospective study the incidence of laryngopharyngeal symptoms and signs with GERD and their response to antireflux therapy was established. Eighty-seven percent of patients with laryngopharyngeal complaints had gastroesophageal reflux studied. Statistical analysis: Pearson chi-square test was used for statistical analyses of the comparative studies. A P value of <.05 was considered significant.
Conclusion: In short gastroesophageal reflux disease is a common disease that impairs quality of life. Laryngopharyngeal symptoms are reliable predictors of GERD. With increased number of GERD symptoms one should be aware of the most common symptoms so as to institute early therapy.
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