Abstract
Objective: To evaluate the effectiveness of 0.5% hydrogen peroxide (H2O2) irrigation in hemostasis after adenoidectomy.
Method: A cross-sectional study was conducted on 80 children undergoing adenoidectomy. Children were randomized into either 0.5% H2O2 or control (25 0C serum physiologic) irrigation groups after adenoidectomy. Adenoid volume, size, location were recorded. Hemostasis and operation times were measured. Bleeding and hemostasis visual analog scale (VAS) values were scored.
Results: The ages ranged from 3 to 9 years (mean ± SD, 4.9 ± 1.8 years). There were 29 boys and 8 girls in the control group and 22 boys and 21 girls in the H2O2 group. The average hemostasis time for H2O2 group (4 minutes) was shorter than control group (5 minutes), but there was no correlation between control and H2O2 groups with respect to operation (P = .854) or hemostasis time (P = .065), or VAS values of subjective bleeding (P = .961) and hemostasis (P = .346). Significant positive correlation was found between adenoid volume and operation time (r = 0.269; P = .016). But correlation between adenoid volume and hemostasis was not significant (r = 0.213; P = .058).
Conclusion: We may recommend to surgeons a higher concentration than 0.5% H2O2 in the hemostasis of post- adenoidectomy, especially for those confronted with significant bleeding following adenoidectomy.
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