Abstract
Objective: Evaluation of the result of treatment with total laryngectomy and complementary radiotherapy in patients with cancer of the larynx in stage T3- T4 N0M0. Analysis of the impact of the primary cancer localization, feature G and T, unradical result of the surgery treatment.
Method: The study population included 136 patients with cancer of the larynx in stadium T3-T4 N0M0 treated with curative intent by total laryngectomy with complementary radiotherapy. T3 was in 61 patients, T4 was in 75 patients.
Results: In coregression analysis of multivariate failure did not show the statistically related to the recurrence and death P > 0.1. Two- and 5-year disease-free survival was for all group adequately 83% and 76%. Two- and 5-year disease-free survival in cases T3 and T4 was adequately 88% and 76%. In patients with primary localization in glottis 2- and 5-year disease-free survival was adequately 81% and 73% in cases supraglottis 88% and 81%.
Conclusion: The primary cancer localization, feature G and T, unradical result of the surgery does not statistically relate to the result of the treatment by laryngectomy with complementary radiotherapy. Total laryngectomy with complementary radiotherapy has high finish result of treatment cancer of the larynx in stage T3-T4 N0 M0.
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