Screening for Lesions with an Oral Mucosal Brush Biopsy

Abstract

Objective: Evaluate the use and impact of providing a noninvasive oral brush biopsy to patients presenting on an initial visit with a mildly or nonsuspicious oral lesion. The cytopathologic findings can be used as confirmatory evidence in support of the clinical impression.

Method: The brush biopsy test provided an option to patients presenting nonsuspicious lesions at our office over a 24-month period. Impressions regarding obtaining a specimen and time required were monitored. When brush biopsy tests were ordered, cytologic evaluation was performed. Doctors were surveyed on their impressions of the test.

Results: The brush biopsy test was performed on patients with mildly to nonsuspicious lesions. Cytology evaluation was performed, and abnormal or dysplastic cells were reported. Results showed how the brush biopsy cytology confirmed the clinical impressions. Survey of clinicians indicated that tests were relatively easy to perform and could be completed in a reasonable timeframe of less than 10 minutes during the initial visit. Doctors reported benefits of ease of performance, absence of identifiable risks, and complications from the tests.

Conclusion: Oral brush biopsy can be provided to patients as a screening option for oral mucosal lesions that are not highly suspicious. Surveys indicated the test was perceived as an instrument to provide confidence to patients and gather information early with no complications and risk factors during the visit.