Abstract
Objective: By analyzing the difference of clinical manifestations, such as MAST results, total IgE, and Eosinophil count, before and after IT in AR patients who have been sensitized to the Df allergen, this research tried to find out about the character of the treatment response.
Method: The study included 192 patients, excluding one patient who stopped therapy during the process. After dividing the group by the duration of therapy and the degree of sensitization to the Df, the MAST, total IgE, and eosinophil count of each group were compared before and at least 6 months after therapy.
Results: After dividing the subjects into different groups according to the duration of IT into the 6 to 12-months group (n = 136) and the more than 12-months group (n = 56), the latter group showed a significant reduction in the Df specific antibody IgE, Dermatophagoides pteronyssinus (Dp) specific antibody IgE, and eosinophil count.
Conclusion: In conclusion, immunotherapy has greater treatment response in patients with a more severe degree of sensitization to the Df allergen and the duration of treatment for more than 1 year.
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