Abstract
Objective: Analyze the role of Staphylococcus aureus enterotoxins (SEs) in the pathogenesis of chronic rhinosinusitis (CRS) with and without nasal polyps (CRSwNP and CRSsNP).
Method: Forty patients with CRSwNP, 30 patients with CRSsNP, and 30 healthy controls were enrolled in the study. Serum specific IgE against SEA, SEB, and SEC was measured using ImmunoCAP 100E system, and statistical analysis was performed by SPSS 13.0 software.
Results: The serum level of specific IgE to SEB in patients with CRSwNP or CRSsNP was significantly higher than that in controls, respectively (P = .05).
Conclusion: Staphylococcal superantigen SEB may play a role in the development of CRS with or without nasal polyps.
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