Abstract
Objective: The current study updated our previous study involving the outcomes and prognostic factors of sinonasal cancer patients treated at our institution.
Method: A total of 183 sinonasal cancer patients who were treated between 1974 and 2008 with a minimum follow-up of 2 years were retrospectively reviewed and restaged using the seventh edition of the AJCC staging manual.
Results: The mean age was 60.89 years (+14.99 years SD), 70.4% males. Tumor stage distribution was: T1:72patients; T2:48p; T3:39p; T4:24p. Ninety-six patients received surgery as primary treatment, 51 received surgery plus radiotherapy, 7 received surgery plus radiotherapy with/without chemotherapy, and 22 received radiotherapy with/without chemotherapy palliative treatment. The 1-, 5-, 10-year disease free survival rate was 82.3%, 49%, and 34.9%, respectively. There was no significant survival difference between surgery alone and surgery plus radiotherapy. The parameters with statistical prognostic significance were tumor stage, tumor histology, and locoregional failure.
Conclusion: Although there is a significant advance in survival rates, the failure at the primary site is still the main problem. As a prognostic value of survival, therefore, we should put all our effort to improve the control of the locoregional failure.
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