Abstract
Objective: Evaluate the oncologic outcome and functional results of SCPL with CHEP or CHP in selected cases of glottic/supraglottic carcinoma recurrence after primary (surgery or radiotherapy) treatment.
Method: Retrospective analysis of medical records. Twenty-three consecutive patients treated with salvage intent by SCPL from 1998 to 2007 were collected. Main outcomes measures were recurrence, overall survival, disease-specific survival, cause of death, and functional results.
Results: Most of our patients were males (20/86.9%), with a mean age of 57 years. Eighteen (78%) were primarily treated with endoscopic laser resection, while 5 (22%) patients received external beam radiation. Disease-free interval ranged between 2 and 59 months (mean, 10.2 months) after primary treatment and recurrence. SCL-CHEP was carried out in 20 patients, whereas 3 patients underwent SCL-CHP. Tracheostomy tube was removed in 20 patients (86.9%) between 7 and 300 days (mean, 30.1 days) after surgery. Mean swallowing recovery time was 9 days (range 7 to 185 days) and was achieved in 20 patients (86.9%). The 5-year overall survival was 82.6%
Conclusion: SCPL with CHEP/CHP is a feasible, oncologically safe, functionally valid alternative to total laryngectomy in selected laryngeal recurrence.
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