Breaching Host Defenses in the Normal Respiratory Tract

1. Ball F , Canary JJ , and Kyle LH : Tissue changes during intermittent starvation and caloric restriction as treatment for severe obesity. Arch. Intern. Med. 125: 62–68, 1970.

2. Benoit FL , Martin RL , and Watten RH : Changes in body composition during weight reduction in obesity. Balance studies comparing effects of fasting and a ketogenic diet. Ann. Intern. Med 63: 604–612, 1965.

3. Bloom WL : Fasting as an introduction to the treatment of obesity. Metabolism 8: 214–220, 1959.

1. Proctor DF : The upper airway. I. Nasal physiology and defense of the lungs. Am. Rev. Resp. Dis. 115: 437–130, 1977.

2. Proctor DF , Andersen I , Lundquist, GR : Human nasal mucosal function at controlled temperatures. Resp. Physiol. 30: 109–124, 1977.

3. Dalhamn T , and Sjoholm J : Studies on SO2, NO2, and NH3: effect on ciliary activity in rabbit trachea of single in vitro exposure and resorption in rabbit nasal cavity. Acta Physiol. Scand. 58: 287–291, 1963.

4. I am indebted to Dr. Abraham I. Braude for this important concept.

5. Gibbons RJ , and Van Houte J : Bacterial adherence in oral microbial ecology. Ann Rev. Microbiol. 29: 19–44, 1975.

6. Irwin RS , Rosen MJ , and Braman SS : Cough: a comprehensive review. Arch. Intern. Med. 137: 1186–1191, 1977.

7. Green GM , Jakab GJ , Low RB , Cavis GS : Defense mechanisms of the respiratory membrane. Am. Rev. Resp. Dis. 115: 479–505, 1977.

8. Blake J : On the movement of mucus in the lung. J. Biochem. 8: 179–190, 1975.

9. Okeson GC , and Divertie MB : Cilia and bronchial clearance: the effects of pharmacologic agents and disease. Mayo Clin. Proc. 45: 361–373, 1970.

10. Wanner A : Clinical aspects of mucociliary transport. Am. Rev. Resp. Dis. 116: 73–125. 1977.

11. Litt M : Mucus rheology: relevance to mucociliary transport. Arch. Intern. Med. 126: 417–423, 1970.

12. Guidotti TL : The inhaled higher oxides of nitrogen-inhalation toxicology. Environ, Res., in press, 1978.

13. Dannenberg AM Jr : Macrophages in inflammation and infection. N. Engl. J. Med. 293: 489–493, 1975.

14. Dannenberg AM Jr et al: Macrophage activation in tuberculous lesions. Excerpta Medica Congress Series No. 325 pp. 223–235, 1973.

15. Unanue ER : Secretory function of mononuclear phagocytes. Am. J. Pathol. 83: 396–417, 1976.

16. Dannenberg AM : Influence of environmental factors on the respiratory tract-summary and prespectives. J. Reticuloendothelial. Soc. 22: 273–290, 1977.

17. Sorokin SP : Properties of alveolar cells and tissues that strengthen alveolar defenses. Arch. Intern. Med. 126: 450–463, 1970.

18. Barton AD et al: Mucus glycoprotein content of chronic bronchitis sputum. Proc. Soc. Exp. Biol. Med. 156: 8–13, 1977.

19. Martin RR , and Warr GA : Cigarette smoking and human pulmonary macrophages. Hospital Practice: 97–104, 1977.

20. Schilling RSF et al: Lung function, respiratory disease, and smoking in families. Am. J. Epidemiol. 106: 274–283, 1977.

21. Gluckman SJ , Dvorak VS , MacG regor RR : Host defenses during prolonged alcohol consumption in a controlled environment. Arch. Intern. Med. 137: 1539–1543, 1977.

22. Holma B , Lindegren M , Andersen JM : pH effects on ciliomotility and morphology of respiratory mucosa. Arch. Environ. Health 32: 216–226, 1977.

23. Proctor DF , Andersen I , Lundqvist GR : Human nasal mucosal function at controlled temperatures. Resp. Physiol. 30: 109–124, 1977.

24. Blair HT : Effects of Rhinovirus infection on pulmonary function of healthy human volunteers. Am. Rev. Resp. Dis. 114: 95–102, 1976.

25. Jakab GJ , Green GM : Defect in intracellular killing of Staphylococcus aureus within alveolar macrophages in Sendai virus-infected murine lungs. J. Clin. Invest. 57: 1533–1539, 1976.