Optimizing cognitive development over the life course and preventing cognitive decline: Introducing the Cognitive Health Environment Life Course Model (CHELM)

Abstract

Optimal cognitive development is defined in this article as the highest level of cognitive function reached in each cognitive domain given a person’s biological and genetic disposition, and the highest possible maintenance of cognitive function over the adult life course. Theoretical perspectives underpinning the development of a framework for understanding optimal cognitive development are described, including differential development, intra-individual dynamics, cascades, biological mechanisms, reserve capacity, and plasticity. The Cognitive Health and Environment Life Course Model (CHELM) is proposed as a means to provide a framework for understanding the socio-demographic, lifestyle, and health factors influencing cognitive development and decline. The CHELM may guide framing of policy and interventions to optimize cognitive development and minimize cognitive decline in late-life.

Keywords

cognitive decline cognitive development dementia life course plasticity risk factors

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