When the Toxic Substances Control Act (TSCA) was passed by the US Congress in 1976, its advocates pointed to new generation of genotoxicity tests as a way to systematically screen chemicals for carcinogenicity. However, in the end, TSCA did not require any new testing of commercial chemicals, including these rapid laboratory screens. In addition, although the Environmental Protection Agency was to make public data about the health effects of industrial chemicals, companies routinely used the agency’s obligation to protect confidential business information to prevent such disclosures. This paper traces the contested history of TSCA and its provisions for testing, from the circulation of the first draft bill in the Nixon administration through the debates over its implementation, which stretched into the Reagan administration. The paucity of publicly available health and environmental data concerning chemicals, I argue, was a by-product of the law and its execution, leading to a situation of institutionalized ignorance, the underside of regulatory knowledge.
BoudiaSorayaJasNathalie, eds. 2013. Toxicants, Health and Regulation since 1945. London, UK: Pickering & Chatto.
2.
BoudiaSorayaJasNathalie, eds. 2014. Powerless Science? Science and Politics in a Toxic World. New York: Berghahn Books.
3.
BoullierHenriDemortainDavidZeemanMaurice. 2019. “Inventing Prediction for Regulation: The Development of (Quantitative) Structure-Activity Relationships for the Assessment of Chemicals at the US Environmental Protection Agency.” Science & Technology Studies32 (4): 137–57.
4.
BoydWilliam. 2017. “Genealogies of Risk: Environmental Law in a Time of Displacement, 1980s–2000s.” Davis Center Paper, Princeton University, Princeton, NJ.
5.
BoylandE.1967. “The Correlation of Experimental Carcinogenesis and Cancer in Man.” Progress in Experimental Tumor Research11 (1967): 222–34.
6.
BrickmanRonaldJasanoffSheilaIlgenThomas. 1985. Controlling Chemicals: The Politics of Regulation in Europe and the United States. Ithaca, NY: Cornell University Press.
7.
CEQ (Council on Environmental Quality). 1970. Environmental Quality: The First Annual Report of the Council on Environmental Quality, Together with the President’s Message to Congress. Washington, DC: US Government Printing Office.
8.
CEQ (Council on Environmental Quality). 1971a. The President’s 1971 Environmental Program. Washington, DC: US Government Printing Office.
9.
CEQ (Council on Environmental Quality). 1971b. Toxic Substances. Washington, DC: US Government Printing Office.
10.
CEQ (Council on Environmental Quality). 1972. Environmental Quality: Third Annual Report of the Council on Environmental Quality. Washington, DC: US Government Printing Office.
11.
ClaxtonLarry D.UmbuzeiroGisela de A.DeMariniDavid M.. 2010. “The Salmonella Mutagenicity Assay: The Stethoscope of Genetic Toxicology for the 21st Century.” Environmental Health Perspectives118 (11): 1515–22.
12.
CornJacqueline Karnell. 1989. Protecting the Health of Workers: The American Conference of Governmental Industrial Hygienists, 1938–1988. Cincinnati, OH: American Conference of Governmental Industrial Hygienists.
13.
CranorCarl F.2011. Legally Poisoned: How the Law Puts Us at Risk from Toxicants. Cambridge, MA: Harvard University Press.
14.
CranorCarl F.2017. Tragic Failures: How and Why We Are Exposed to Toxic Chemicals. New York: Oxford University Press.
15.
CreagerAngela N. H.2014. “The Political Life of Mutagens: A History of the Ames Test.” In Powerless Science? edited by BoudiaS.JasN., 46–64. New York: Berghahn.
16.
DaviesJ. Clarence. 2009. “The Toxic Substances Control Act from the Perspective of J. Clarence Davies.” Interview by Jody A. Roberts and Kavita D. Hardy, Transcript #0640, Science History Institute, Philadelphia, PA.
17.
DemortainDavid. 2019. The Science of Bureaucracy: Risk Decision-making and the US Environmental Protection Agency. Cambridge, MA: The MIT Press.
18.
DenisonRichard A.2004. Orphan Chemicals in the HPV Challenge: A Status Report. Washington, DC: Environmental Defense Fund.
EPA (Environmental Protection Agency). 1979. “Toxic Substances Control: Premarket Notification Requirements and Review Procedures.” Federal Register44 (January 10): 2242–348.
21.
EPA (Environmental Protection Agency). 1982. “Toxic Substances Control Act (TSCA) Report to Congress for Fiscal Year 1981.” National Service Center for Environmental Publications No. 560182100.
FortunKim. 2004. “Environmental Information Systems as Appropriate Technology.” Design Issues20 (3): 54–65.
25.
FortunKim. 2009. “Environmental Right-to-know and the Transmutations of Law.” In Catastrophe: Law, Politics, and the Humanitarian Impulse, edited by SaratAustinLezaunJavier, 146–71. Amherst, MA: University of Massachusetts Press.
26.
FrickelScott. 2004. Chemical Consequences: Environmental Mutagens, Scientist Activism, and the Rise of Genetic Toxicology. New Brunswick, NJ: Rutgers University Press.
27.
FrickelScottEdwardsMichelle. 2014. “Untangling Ignorance in Environmental Risk Assessment.” In Powerless Science? edited by BoudiaS.JasN., 215–33. New York: Berghahn.
28.
FrickelScottGibbonSahraHowardJeffKempnerJoannaOttingerGwenHessDavid J.. 2010. “Undone Science: Charting Social Movement and Civil Society Challenges to Research Agenda Setting.” Science, Technology, & Human Values35 (4): 444–73.
29.
“From Microbes to Men: The New Toxic Substances Control Act and Bacterial Mutagenicity/Carcinogenicity Tests.” 1976. Environmental Law Reporter6 (November): 10248–52.
30.
GaynorKevin. 1977. “The Toxic Substances Control Act: A Regulatory Morass.” Vanderbilt Law Review30 (6): 1149–96.
31.
GrisingerJoanna. 2012. The Unwieldy American State: Administrative Politics since the New Deal. Cambridge, UK: Cambridge University Press.
32.
HaysSamuel P.1987. Beauty, Health, and Permanence: Environmental Politics in the United States, 1955–1985. Cambridge, UK: Cambridge University Press.
33.
Hepler-SmithEvan. 2019. “Molecular Bureaucracy: Toxicological Information and Environmental Protection.” Environmental History24 (3): 534–60.
34.
HigginsonJ.1969. “Present Trends in Cancer Epidemiology.” In 8th Proceedings of the Canadian Cancer Conference, edited by MorganJ. F., 40–75. New York: Pergamon Press.
35.
JaeschkeWayne C.1978. “The Toxic Substances Control Act.” Research Management21 (1): 14–16.
36.
JasNathalie. 2014. “Gouverner les substances chimiques dangereuses dans les espaces internationaux.” In Le gouvernement des technosciences. Gouverner le progrès et ses dégâts depuis 1945, edited by PestreDominique, 31–63. Paris, France: La Découverte.
37.
JasanoffSheila. 1990. The Fifth Branch: Science Advisers as Policymakers. Cambridge, MA: Harvard University Press.
38.
JellinekSteven D.2010. “The Toxic Substances Control Act: From the Perspective of Steven D. Jellinek.” Interview by Jody A. Roberts and Kavita D. Hardy, Transcript #0653, Science History Institute, Philadelphia, PA.
39.
KneeseAllen V.SchulzeWilliam D.. 1977. “Environment, Health, and Economics—The Case of Cancer.” The American Economic Review67 (1): 326–32.
KrimskySheldon. 2017. “The Unsteady State and Inertia of Chemical Regulation under the U.S. Toxic Substances Control Act.” PLoS Biology15 (12): e2002404.
42.
Library of Congress. 1976. Legislative History of the Toxic Substances Control Act. Washington, DC: US Government Printing Office.
43.
LuttsRalph H.1985. “Chemical Fallout: Rachel Carson’s Silent Spring, Radioactive Fallout, and the Environmental Movement.” Environmental Reviews9 (3): 210–25.
44.
LyndonMary L.1989. “Information Economics and Chemical Toxicity: Designing Laws to Produce and Use Data.” Michigan Law Review87 (7): 1795–861.
45.
LyndonMary L.2012. “The Toxicity of Low-dose Chemical Exposures: A Status Report and a Proposal.” Jurimetrics52 (4): 457–500.
46.
MazurekJanClarence DaviesJ.. 1998. Pollution Control in the United States: Evaluating the System. Washington, DC: Resources for the Future.
47.
McCubbinsMathew D.NollRoger G.WeingastBarry R.. 1987. “Administrative Procedures as Instruments of Political Control.” Journal of Law, Economics, & Organization3 (2): 243–77.
48.
Nemkov, Peter M. Letter to Karl A. Hochschwender. 1972. “Re: D. 3419, the ‘Consumer Product Safety Act;’ S. 1478, the ‘Toxic Substances Control Act of 1972;’ and S. 3970, the ‘Consumer Executive Organization Act of 1972,’” October 25. Accessed April 26, 2021. https://www.toxicdocs.org/d/914bVq2q0ODMXLRYq0QVxjoz6
49.
Office of Technology Assessment. 1983. The Information Content of Premanufacture Notices: Background Paper. Washington, DC: US Government Printing.
50.
O’ReillyJames T. 2010. “Torture by TSCA: Retrospectives of a Failed Statute.” Natural Resources & Environment25 (1): 43–44, 47.
51.
OttingerGwenCohenBenjamin R., eds. 2011. Technoscience and Environmental Justice: Expert Cultures in a Grassroots Movement. Cambridge, MA: The MIT Press.
52.
PallemaertsMarc. 2003. Toxics and Transnational Law: International and European Regulation of Toxic Substances as Legal Symbolism. Oxford, UK: Hart.
53.
ProctorRobert N.SchiebingerLonda, eds. 2008. Agnotology: The Making and Unmaking of Ignorance. Stanford, CA: Stanford University Press.
54.
QuarlesJohn. 1976. Cleaning Up America: An Insider’s View of the Environmental Protection Agency. Boston, MA: Houghton Mifflin.
55.
ReichMichael R.SpongJaquelin K.. 1983. “Kepone: A Chemical Disaster in Hopewell, Virginia.” International Journal of Health Services13 (2): 227–46.
56.
RichterLaurenCordnerAlissaBrownPhil. 2018. “Non-stick Science: Sixty Years of Research and (In)Action on Fluorinated Compounds.” Social Studies of Science48 (5): 691–714.
57.
SchefflerRobin Wolfe. 2019. A Contagious Cause: The American Hunt for Cancer Viruses and the Rise of Molecular Medicine. Chicago, IL: The University of Chicago Press.
58.
SellersChristopher C.2012. Crabgrass Crucible: Suburban Nature and the Rise of Environmentalism in Twentieth-century America. Chapel Hill, NC: University of North Carolina Press.
59.
SilbergeldEllen K.MandrioliDanieleCranorCarl F.. 2015. “Regulating Chemicals: Law, Science, and the Unbearable Burdens of Regulation.” Annual Review of Public Health36 (1): 175–91.
60.
StadlerLinda. 1993. “Corrosion Proof Fittings v. EPA: Asbestos in the Fifth Circuit—A Battle of Unreasonableness.” Tulane Environmental Law Journal6 (2): 423–38.
61.
Swetonic, M. M. Letter to J-M Environmental Health Task Force, AIA/NA Board of Directors and Administrative Sub-Committee. 1971. “Update on Various Federal Government Activities,” November 22. Accessed April 26, 2010. https://www.toxicdocs.org/d/EbajZE95mBbGk715gkEKVpRV.
62.
US Congress House of Representatives. 1979. Authorizations and Oversight of the Toxic Substances Control Act: Hearings before the Subcommittee on Consumer Protection and Finance of the Committee on Interstate and Foreign Commerce, House of Representatives, 96th Congress, 1st session, on H.R. 2606, March 8, 13, and 20, 1979. Washington, DC: US Government Printing Office.
63.
US Congress Senate. 1972. The Toxic Substances Control Act of 1971 and Amendment: Hearings before the Subcommittee on the Environment of the Committee on Commerce, United States Senate, 92nd Congress, 1st Session, on S. 1478, Aug. 3, 4, 5, Oct. 4, and Nov. 5, 1971, Vol. 3. Washington, DC: US Government Printing Office.
64.
US Congress Senate. 1975. Toxic Substances Control Act: Hearings before the Subcommittee on the Environment of the Committee of Commerce, United States Senate, 94th Congress, 1st Session, on S. 776, March 3, 5, 10, and April 15, 1975. Washington, DC: US Government Printing Office.
65.
US Congress Senate. 1984. Toxic Substances Control Act Oversight: Hearings before the Subcommittee on Toxic Substances and Environmental Oversight of the Committee on Environment and Public Works, United States Senate, 98th Congress, 1st Session, July 27, 29, and August 1, 1983. Washington, DC: US Government Printing Office.
66.
US GAO (US General Accounting Office). 1994. “Toxic Substances Control Act: Legislative Changes Could Make the Act More Effective.” GAO/RCED-94-103, US GAO, Washington, DC.
67.
US GAO (US Government Accountability Office). 2007. “Comparison of US and Recently Enacted European Union Approaches to Protect against the Risks of Toxic Chemicals.” GAO-07-825, US GAO, Washington, DC.
68.
US GAO (US Government Accountability Office). 2009. “Chemical Regulation: Options for Enhancing the Effectiveness of the Toxic Substances Control Act.” GAO-09-428T, US GAO, Washington, DC.
69.
VaughanSteven. 2012. “Review of the Toxic Substances Control Act: A Practical Guide by Miriam V. Gold and Jean Warshaw.” Journal of Environmental Law24 (3): 581–84.
70.
VogelSarah A.2013. Is It Safe? BPA and the Struggle to Define the Safety of Chemicals. Berkeley, CA: University of California Press.
71.
WadeNicholas. 1971. “Special Virus Cancer Program: Travails of a Biological Moonshot.” Science174 (4016): 1306–11.
72.
WagnerWendy E.2004. “Commons Ignorance: The Failure of Environmental Law to Produce Needed Information on Health and the Environment.” Duke Law Journal53 (6): 1619–744.
73.
WellfordHarrison. 1972. “Pesticides.” In Nixon and the Environment: The Politics of Devastation; Thirteen Essays, edited by RathlesbergerJames, 145–62. New York: Taurus Communications.
74.
WhortonJames C.1974. Before Silent Spring: Pesticides and Public Health in Pre-DDT America. Princeton, NJ: Princeton University Press.
