Metabolic and Intestinal Effects of Short-Chain Fatty Acids

Cummings JH : Colonic absorption: The importance of short chain fatty acids in man . Scand J Gastroenterol20:88-99, 1984

Demigné C. , Remesy C. : Stimulation of absorption of volatile fatty acids and minerals in the cecum of rats adapted to a very high fiber diet. J Nutr115:53-60, 1985

Cummings JH , Pomare EW , Branch WJ : Short chain fatty acids in human large intestine, portal, hepatic, and venous blood. Gut28:1221-1227, 1987

Yang MG , Manoharen K. , Mickelsen O. : Nutritional contributions of volatile fatty acids from the cecum of rats. J Nutr100:545-550, 1970

Cummings JH : Short chain fatty acids in the human colon. Gut22:763-779, 1981

Roediger WEW , Rae DA : Trophic effect of short chain fatty acids on mucosal handling of ions by the defunctionalized colon. Br J Surg69:23-25, 1982

Sakata T. : Stimulatory effect of short chain fatty acids on epithelial cell proliferation in the rat intestine: A possible explanation for the trophic effects of fermentable fiber, gut microbes and luminal trophic effects. Br J Nutr58:95-103, 1987

Kripke SA , Fox AD , Berman JM , et al: Stimulation of intestinal mucosal growth with intracolonic infusion of short chain fatty acids. JPEN13:109-116, 1989

Scheppach W. , Richter A. , Liepold H. , et al: The effect of short-chain fatty acids on cecal crypt proliferation in man. JPEN, in press

Rombeau JL , Kripke SA , Settle RG : Short-chain fatty acids: Production, absorption, metabolism, and intestinal effects. IN Dietary Fiber, 2nd ed., Kritchevsky D (ed). Plenum Press, New York, 1990, pp 317-337

Czerkawski JW : Energetics of rumen fermentation. IN An Introduction to Rumen Studies. Pergamon Press, Oxford, 1986, pp 85-101

Wrong OM : Carbohydrates. IN The Large Intestine: Its Role in Mammalian Nutrition and Homeostasis, Wrong OM , Edmonds CJ , Chadwick VS , eds. Halsted Press, New York, 1981, pp 107-112

Wolin MJ : Interactions between the bacterial species of the rumen. IN Digestion and Metabolism in the Ruminant, McDonald IW , Warner AC , eds. University of New England Pub, Armidale, Australia, 1975, pp 134-148

Englyst HN , Trowell H. , Southgate DAT , et al: Dietary fiber and resistant starch. Am J Clin Nutr46:873-874, 1987

Ravich WJ , Bayless TM , Thomas M. : Fructose: Incomplete intestinal absorption in humans. Gastroenterology84:26-29, 1983

Wolin MJ , Miller TL : Interactions of microbial populations in cellulose fermentations. Fed Proc42:109-113, 1983

Hoverstad T. : Studies of short chain fatty acid absorption in man. Scand J Gastroenterol21:257-260, 1986

Stevens CE , Argenzio RA , Clemens ET : Microbial digestion: Rumen versus large intestine. IN Digestive Physiology and Metabolism in Ruminants, Ruckebusch Y , Thivend P , eds. Avi Pub Co, Westport, CT, 1980, pp 685-706

Smyth DH , Taylor CB : Intestinal transfer of short chain fatty acids in-vitro. J Physiol (Lond)141:73-80, 1958

Ruppin H. , Bar-Meir S. , Soergel KH , et al: Absorption of short chain fatty acids by the colon. Gastroenterology78:1500-1507, 1980

Umesaki Y. , Yajima T. , Yokokura T. , et al: Effect of organic acid absorption on bicarbonate transport in rat colon. Pfugers Arch Ges Physiol379:43-47, 1979

Argenzio RA , Whipp SC: Inter-relationship of sodium, chloride, bicarbonate and acetate transport by the colon of the pig. J Physiol (Lond)295:365-381, 1979

Engelhardt W. , Rechkemmer G. : Absorption of inorganic ions and short chain fatty acids in the colon of mammals. IN Intestinal Transport: Fundamental and Comparative Aspects, Gilles-Baillein M , Gilles R , eds. Springer-Verlag, Berlin, 1983, pp 26-45

Engelhardt W. , Rechkemmer G. : The physiological effects of short chain fatty acids in the hind gut. Bull R Soc NZ20:149-155, 1983

Hoverstad T. , Bohmer T. , Fausa O. : Absorption of short chain fatty acids from the human colon measured by the 14CO2 breath test. Scand J Gastroenterol17:373-378, 1982

Roediger WEW : Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut21:793-798, 1980

Marty JF , Vernay MY . Abravanel GM : Acetate absorption and metabolism in the rabbit hind-gut. Gut26:562-569, 1985

Ardawi MSM , Newsholme EA : Fuel utilization in colonocytes of the rat . Biochem J231:713, 1985

Buckley BM , Williamson DH : Origins of blood acetate in the rat. Biochem J166:539-545, 1977

Herrmann DBJ , Herz R. , Frolich J. : Role of gastrointestinal tract and liver in acetate metabolism in rat and man. Eur J Clin Invest15:221-226, 1985

Desmoulin F. , Canioni P. , Cozzone PJ : Glutamate-glutamine metabolism in the perfused rat liver: 13C-NMR study using (2-13C-enriched acetate). FEBS Lett184:29-32, 1985

Cross TA , Paul C. , Oberhansli R. : Ketogenesis in the living rats followed by 13C-NMR spectroscopy. Biochemistry23:6398-6402, 1984

Grohn Y. : Propionate loading test for liver function during experimental liver necrosis in sheep. Am J Vet Res46:952-958, 1985

Settle RG : Short chain fatty acids and their potential role in nutritional support . JPEN12:104S-107S, 1988

Cummings JH , Branch WJ : Fermentation and the production of short chain fatty acids in the human large intestine. IN Dietary Fiber: Basic and Clinical Aspects, Vahouny GB , Kritchevsky D , eds. Plenum Press, New York , 1986, pp 131-152

McNeill NI , Cummings JH James WPT : Short chain fatty acid absorption by the human large intestine. Gut19:819-822. 1978

Kvietys PR Granger ND : Effect of volatile fatty acids on blood flow and oxygen uptake by the dog colon. Gastroenterology80:962-969, 1981

Harada E. , Kato S. : Effect of short-chain fatty acids on the secretory response of the ovine exocrine pancreas. Am J Physiol244:G284-G290, 1983

Koruda MJ , Rolandelli RH , Settle RG , et al: The effect of short chain fatty acids on the small bowel mucosa (abstr)JPEN11(suppl):8S, 1987

Rolandelli RH , Koruda MJ , Settle RG , et al: Effects of intraluminal infusion of short chain fatty acids on the healing of colonic anastomosis in the rat. Surgery100:198-203, 1986

Koruda MJ , Rolandelli RH , Bliss DZ , et al: The effect of parenteral nutrition supplemented with short chain fatty acids on the small bowel mucosa in the normal rat. Am J Clin Nutr51:685-689, 1990

Koruda MJ , Rolandelli RH Settle RG : Effect of parenteral nutrition supplemented with short chain fatty acids on adaptation to massive small bowel resection. Gastroenterology95:715-720, 1988

Harig JM , Soergel KH : Treatment of diversion colitis with short chain fatty acid (SCFA) irrigation . N Engl J Med320:23-28, 1989

De Silva HJ , Ireland A. , Kettlewell M. , et al: Short-chain fatty acid irrigation in severe pouchitis (letter). N Engl J Med20:1416, 1989