Selenium and Vitamin E Stability in Parenteral Solutions

Abstract

Stability of α-tocopherol acetate and selenium in amino acid/dextrose solutions with SoluZyme or MVI-1000 vitamin injections was evaluated following exposure to fluorescent lighting and room temperature, and after flowing through an infusion apparatus. The stability of selenium in parenteral solutions for a 10-wk period was also determined. In each condition no significant loss of α-tocopherol acetate or selenium was observed. It was concluded that α-tocopherol acetate and selenium as selenious acid are stable in parenteral solutions and no significant loss occurs during delivery to patients. (Journal of Parenteral and Enteral Nutrition 9:568-570, 1985)