In order to eliminate wasting vials of urokinase, 5000 U/ml aliquots were reconstituted and frozen. The urokinase remained effective for clearing thrombosed catheters for as long as 9 months. When catheters become occluded, patency can be restored by previously frozen urokinase. (Journal of Parenteral and Enteral Nutrition8:298-299, 1984)
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References
1.
Stillman R., Soleman F., Carcia L., et al: Etiology of catheter associated sepsis-correlation with thrombogenicity . Arch Surg112:1497-1499, 1977
2.
Hurtubise M. , Bottino J., Lawson M., et al: Restoring patency of occluded central venous catheters. Arch Surg115:212-213, 1980
