The present study was directed at determining whether or not a relatively low-calorie regimen in which 40 to 50% of the calories are provided as fat will produce positive nitrogen balance in most patients, and at establishing the electrolyte requirements for such a regimen. Clearly, the recommended regimen is successful in promoting nitrogen balance and provides adequate electrolytes. Further experience will be necessary to determine the place of intravenous fat emulsions in the clinical practice of total parenteral nutrition.
Get full access to this article
View all access options for this article.
References
1.
1. Thompson WR: Peripheral venous TPN in the treatment of critically ill surgical patients, IN Meng HC, Wilmore DW (eds): Fat Emulsions in Parenteral Nutrients, AMAChicago, 1976, p. 19, 61, 62
2.
2. Blanchard RJ, Gillespie PJ: Some comparisons between fat emulsion and glucose for parenteral nutrition in adults, The Wirreng Health Science Center, p. 2–13
3.
3. Long JM III: Use of intravenous fat emulsion after trauma and burn, IN Meng HC, Wilmore DW (eds): Fat Emulsions in Parenteral Nutrition, AMAChicago, 1976, p. 76–79
4.
4. Jeejeebhoy KN, Marliss EB, Anderson GHet al: Lipid in parenteral nutrition: studies of clinical and metabolic features, IN Meng HC, Wilmore DW (eds): Fat Emulsions in Parenteral Nutrition, AMAChicago, 1976, pp. 45–54
5.
5. Zohrab WJ, Mc Hattie JD, Jeejeebhoy KN: Total parenteral alimentation with lipid. Gastroenterol64:583–592, 1973
6.
6. Hansen LM, Hardie WR, Hidalgo J: Fat emulsion for intravenous administration: clinical experience with intralipid 10%, Ann Surg184:80–88, 1976
7.
7. Alexander CS, Zieve L: Fat infusions, Arch Int Med107:514–528, 1961
8.
8. Wretlind A: Modern principles of the use of fat emulsions in parenteral nutrition, IN Parenteral Nutrition Symposium, Wilkerson, London, 1972
9.
9. Halbery D, Schubert O, Wretlind A: Experimental and clinical studies of fat emulsion for intravenous nutrition, IN Parenteral Nutrition, Meng HC, Law D (eds), Symposium, 1970
10.
10. Borresen HC, Coran AG, Knutrud O: Metabolic results of parenteral feeding in neonatal surgery: A balanced parenteral feeding program based on a synthetic L-amino acid solution and a commercial fat emulsion, Ann Surg172:291–301, 1970
11.
11. Edgren B, Wretlind A: Ernährungphysiologische und pharmakologische Gesichtspunkte der Verwendung von Aminosäuren und Fett in der intravenosen Ernahrung (Nutritive physiological and pharmacological aspects of using amino acids and fats for intravenous nutrition). Wien Med Wchnschr117:32–41, 1967
12.
12. Horisberger B: Erste Erfahrungen mit einer 20 prozentigen Fettemulsion in der postoperativen Behandlung (First experience with a 20% fat emulsion in post-surgical treatment). Helv Chir Acta32:48–53, 1965
13.
13. Mac Fadyen BV: Use of a ten percent soybean oil emulsion in adult patients, IN Meng HC, Wilmore DW (eds): Fat Emulsions in Parenteral Nutrition, AMAChicago, 1976, pp. 54–57
14.
14. Blackburn GL: Nitrogen conservation using fat as a non-protein calorie source, IN Meng HC, Wilmore DW (eds): Fat Emulsions in Parenteral Nutrition, AMAChicago, 1976, pp. 65–66
15.
15. Jeejeebhoy KN, Anderson GH, Nakhooda APet al: Metabolic studies in total parenteral nutrition with lipid in man. Comparison with glucose. J Clin Invest57:125–136, 1976
16.
16. Greenberg GR, Marliss EB, Anderson GHet al: Protein-sparing therapy in postoperative patients. Effects of added hypocaloric glucose or lipid. N Engl J Med294:1411–1416, 1976
17.
17. Blackburn GL, Flatt JP, Clowes GHA Jret al: Protein sparing therapy during periods of starvation with sepsis or trauma. Ann Surg177:588–594, 1973
