Pharmacy Update

Anonymous: Change in solubility of insulin in therapeutic mixtures of insulin preparations: HPLC analysis. Diabetes News Digest 1990 Mar:3.

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Olsson PO , Arnqvist H. , Von Schenck H. Miscibility of human semisynthetic regular and Lente insulin and human biosynthetic regular and NPH insulin. Diabetes Care 1987 ; 10:473-77.

Velussi M. , Cergnigoi A. , Puglisi C. , et al. Experimental study of the different potencies of biosynthetic and semisynthetic human insulin mixtures in the treatment of insulin-dependent diabetics. Curr Ther Res 1989;46:390-97.

Klauser R. , Schernthaner G. , Prager R. Mixtures of human intermediate and human regular insulin in type 1 diabetic patients. Diabetes Res Clin Pract 1988;5:185-90.

Berger M. Pharmacokinetics of subcutaneously injected insulin: the miscibility of short-and long-acting insulin preparations. In: Crepaldi G , et al, eds. Diabetes, obesity and hyperlipidemias . New York: Elsevier Science Publishers , 1985:427-31.

Galloway JA , et al. Mixtures of intermediate-acting insulin (NPH and Lente) with regular insulin: an update. In: Skyler JS , ed. Insulin update: 1982. Princeton, NJ: Excerpta Medica, 1982: 111-19.

Nolte MS , et al. Reduced solubility of short-acting soluble insulins when mixed with longer-acting insulins. Diabetes 1983 ;32:1177-81.

Binder C. , et al. Insulin pharmacokinetics. Diabetes Care 1984;7:188-99.

Lauritzen T. , et al. Absorption of isophane (NPH) insulin and its clinical implications. Br Med J 1982 ;285:159.

Galloway JA , et al. Factors influencing the absorption serum insulin concentration, and blood glucose responses after injections of regular insulin and various insulin mixtures. Diabetes Care 1981;3:366-76.

Galloway JA Chemistry and the clinical use of insulin. In: Galloway JA , Potvin JH , Shuman CR , eds. Diabetes mellitus, 9th ed. Indianapolis: Eli Lilly and Company, 1990:ch7.

Jawadi MH , Ho LS Stability and reproducibility of the biological activity of premixed short-acting and intermediate-acting insulins. Am J Med 1986;81:467-71.

Peters AL , Davidson MB Effect of storage on action of NPH and regular insulin mixtures. Diabetes Care 1987;10:799-800.

Kasmer RJ , Walker N. , Hurlburt F. , et al. Sterility of preloaded insulin syringes. Am J Infect Control 1986; 14(4): 180-83.