Leiomyosarcoma of the larynx is an extremely rare entity. This tumor is aggressive and is associated with dismal treatment results. We present a case of leiomyosarcoma of the larynx treated with surgery and postoperative radiotherapy. In this article we also discuss laryngeal leiomyosarcoma's clinical manifestations, associated diagnostic dilemmas, and optimal management, as well as a review of the literature.
References
1.
FrankD.J.Leiomyosarcoma of the larynx. Arch Otorhinolaryngol1941; 34: 493–500.
2.
AbbasA., IkramM., YaqoobN.Leiomyosarcoma of the larynx: A case report. Ear Nose Throat J2005; 84(7): 435–6, 440.
WadhwaA.K., GallivanH., O'HaraB.J.Leiomyosarcoma of the larynx: Diagnosis aided by advances in immunohistochemical staining. Ear Nose Throat J2000; 79(1): 42–6.
11.
FreijiJ.E., GluckmanJ.L., BiddingerP.W., WiotG.Muscle tumors in the parapharyngeal space. Head Neck1992; 14(1): 49–54.
12.
FriedmanI.Neoplasms of the larynx. In: SymmersW.St.C., ed. Systemic Pathology Volume 1: Nose, Throat and Ears. 3rd ed. London: Churchill Livingstone; 1986: 240.
13.
MarioniG., StaffieriC., MarinoF., StaffieriA.Leiomyosarcoma of the larynx. Critical review of the diagnostic role played by immunohistochemistry. Am J Otolaryngol2005; 26(3): 201–6.
14.
ThomasS., McGuffH.S., OttoR.A.Leiomyosarcoma of the larynx. Case report. Ann Otol Rhinol Laryngol1999; 108(8): 794–6.
15.
MarioniG., BottinR., StaffieriA., AltavillaG.Spindle-cell tumours of the larynx: Diagnostic pitfalls. A case report and review of the literature. Acta Otolaryngol2003; 123(1): 86–90.
16.
MindellR.S., CalcaterraT.C., WardP.H.Leiomyosarcoma of the head and neck: A review of the literature and report of two cases. Laryngoscope1975; 85(5): 904–10.
17.
AkcamT., OysulK., BirkentH.Leiomyosarcoma of the head and neck: Report of two cases and review of the literature. Auris Nasus Larynx2005; 32(2): 209–12.
18.
PistersP.W., HarrisonL.B., LeungD.H.Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma. J Clin Oncol1996; 14(3): 859–68.
19.
YangJ.C., ChangA.E., BakerA.R.Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol1998; 16(1): 197–203.
20.
SuitH.D., MankinH.J., WoodW.C.Treatment of patient with stage M0 soft tissue sarcoma. J Clin Oncol1988; 6(5): 854–62.
21.
EggstonA.A., WolfD.Histopathology of the Ear Nose and Throat.Baltimore: Williams and Wilkins; 1947: 959.
22.
WolfowitzB.L., SchamanA.Smooth-muscle tumours of the upper respiratory tract. S Afr Med J1973; 47(27): 1189–91.
23.
KleinsasserO., GlanzH.Myogenic tumours of the larynx. Arch Otorhinolaryngol1979; 225(2): 107–19.
24.
LevineH.L., TubbsR.Nonsquamous neoplasms of the larynx. Otolaryngol Clin North Am1986; 19(3): 475–88.
25.
CarlesD., DevarsF., SaurelJ.[Leiomyosarcoma of the larynx: Presentation of a case.]Rev Laryngol Otol Rhinol (Bord)1992; 113(2): 115–17.
26.
Rowe-JonesJ.M., SolomonsN.B., RatcliffeN.A.Leiomyosarcoma of the larynx. J Laryngol Otol1994; 108(4): 359–62.
27.
McKiernanD.C., WattersG.W.Smooth muscle tumours of the larynx. J Laryngol Otol1995; 109: 77–9.
28.
HelmbergerR.C., CrokerB.P., MancusoA.A.Leiomyosarcoma of the larynx presenting as a laryngopyocele. AJNR Am J Neuroradiol1996; 17(6): 1112–14.
29.
LippertB.M., SchlüterE., ClaassenH., WernerJ.A.Leiomyosarcoma of the larynx. Eur Arch Otorhinolaryngol1997; 254(9-10): 466–9.
30.
ChaeS.W., ChoiG., ChoiC.S., ChoiJ.O.Leiomyosarcoma of thelarynx. J Otolaryngol1999; 28(5): 293–5.
31.
YoshizakiT., HorikawaT., NonomuraA., FurukawaM.Leiomyosarcoma of the larynx. J Laryngol Otol1999; 113(2): 167–9.
32.
PaczonaR., JóriJ., TiszlaviczL., CzignerJ.Leiomyosarcoma of the larynx. Review of the literature and report of two cases. Ann Otol Rhinol Laryngol1999; 108(7 Pt 1): 677–82.
33.
CocksH., QuraishiM., MorganD., BradleyP.Leiomyosarcoma of the larynx. Otolaryngol Head Neck Surg1999; 121(5): 643–6.
34.
PatrocinioJ.A., PatrocinioL.G., MartinsL.P., SilvaA.M.[Leiomyosarcoma of the larynx. One case report.] An Otorrinolaringol Ibero Am2002; 29(3): 229–35.
35.
PretiG., PalontaF., VioneN.Leiomyosarcoma of the larynx. Tumori2003; 89(3): 321–3.
36.
SasakiT., UshioM., OkitaW., UmemuraS.Subglottic leiomyosarcoma of the larynx; a case report. Auris Nasus Larynx2004; 31(2): 165–9.
37.
KainumaK., KikukawaM., ItohT.Leiomyosarcoma of the larynx: Emergency tracheostomy. J Laryngol Otol2001; 115(7): 570–2.
38.
SkoulakisC.E., StavroulakiP., MoschotzopoulosP.Laryngeal leiomyosarcoma: A case report and review of the literature. Eur Arch Otorhinolaryngol2006; 263(10): 929–34.