Impact of Resistant Pathogens on the Treatment of Otitis

Low DE , Pichichero ME , Schaad UB . Optimizing antibacterial therapy for community-acquired respiratory tract infections in children in an era of bacterial resistance. Clin Pediatr (Phila) 2004;43(2):135–51.

Klein JO . Strategies for decreasing multidrug antibiotic resistance: Role of ototopical agents for treatment of middle ear infections. Am J Manag Care 2002;8(14 Suppl):S345–52.

Dagan R. Treatment of acute otitis media—challenges in the era of antibiotic resistance. Vaccine 2000;19(suppl 1):S9–S16.

Ford-Jones EL , Frieberg J , McGeer A , Microbiologic findings and risk factors for antimicrobial resistance at myringotomy for tympanostomy tube placement—a prospective study of 601 children in Toronto. Int J Pediatr Otorhinolaryngol 2002;66(3):227–42.

Darrow DH , Dash N , Derkay CS . Otitis media: Concepts and controversies. Curr Opin Otolaryngol Head Neck Surg 2003;11(6):416–23.

Gehanno P , Panajotopoulos A , Barry B , Microbiology of otitis media in the Paris, France, area from 1987 to 1997. Pediatr Infect Dis J 2001;20(6):570–3.

Dagan R , Hoberman A , Johnson C , Bacteriology and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media. Pediatr Infect Dis J 2001;20(9):829–37.

Kilpi T , Herva E , Kaijalainen T , Bacteriology of acute otitis media in a cohort of Finnish children followed for the first two years of life. Pediatr Infect Dis J 2001;20(7):654–62.

Leskinen K , Hendolin P , Virolainen-Julkunen A , Alloiococcus otitidis in acute otitis media. Int J Pediatr Otorhinolaryngol 2004;68(1):51–6.

Himi T , Kita H , Mitsuzawa A , Effect of Alloiococcus otitidis and three pathogens of otitis media in production of interleukin-12 by human monocyte cell line. FEMS Immunol Med Microbiol 2000:29(2):101–16.

Vijayasekaran S , Thornton R , Prosser K , Alloiococcus otitidis in otitis media. Presented at the annual meeting of the American Society of Pediatric Otolaryngology; April 29, 2007; San Diego.

American Academy of Pediatrics Subcommittee on Management of Acute Otitis Media. Diagnosis and management of acute otitis media. Pediatrics 2004;113(5):1451–65.

Brook I , Gober EA . Antimicrobial resistance in the nasopharyngeal flora of children with acute otitis media and otitis media recurring after amoxicillin therapy. J Med Microbiol 2005;54(Pt 1):83–5.

Pichichero ME . Recurrent and persistent otitis media. Pediatr Infect Dis J 2000;19(9):911–16.

Huebner RE , Wasas AD , Hockman M , Bacterial aetiology of non-resolving otitis media in South African children. J Laryngol Otol 2003;117(3):169–72.

Roland PS , Stroman DW . Microbiology of acute otitis externa. Laryngoscope 2002;112(7 Pt 1):1166–77.

Klein JO . In vitro and in vivo antimicrobial activity of topical ofloxacin and other ototopical agents. Pediatr Infect Dis J 2001;20(1):102–3; discussion 120–2.

Couzos S , Lea T , Mueller R , Effectiveness of ototopical antibiotics for chronic suppurative otitis media in Aboriginal children. A community-based, multicentre, double-blind randomised controlled trial. Med J Aust 2003;179(4):185–90.

Cantrell HF , Lombardy EE , Duncanson FP , Declining susceptibility to neomycin and polymyxin B of pathogens recovered in otitis externa clinical trials. South Med J 2004;97(5):465–71.

Mandel EM , Casselbrant ML , Kurs-Lasky M. Acute otorrhea: Bacteriology of a common complication of tympanostomy tubes. Ann Otol Rhinol Laryngol 1994;103(9):713–18.

Coticchia JM , Dohar JE . Methicillin-resistant Staphylococcus aureus otorrhea after tympanostomy tube placement. Arch Otolaryngol Head Neck Surg 2005;131(10):868–73.

Weber PC , Roland PS , Hannley M , The development of antibiotic resistant organisms with the use of ototopical medications. Otolaryngol Head Neck Surg 2004;130(3 Suppl):S89–94.

Hwang JH , Tsai HY , Liu TC . Community-acquired methicillin-resistant Staphylococcus aureus infections in discharging ears. Acta Otolaryngol 2002;122(8):827–30.

Jang CH , Park SY . Emergence of ciprofloxacin-resistant Pseudomonas in chronic suppurative otitis media. Clin Otolaryngol Allied Sci 2004;29(4):321–3.

Esposito S , D'Errico G , Montanaro C. Topical and oral treatment of chronic otitis media with ciprofloxacin. A preliminary study. Arch Otolaryngol Head Neck Surg 1990;116(5):557–9.

Esposito S , Noviello S , D'Errico G , Montanaro C. Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. Arch Otolaryngol Head Neck Surg 1992;118(8):842–4.

Yuen PW , Lau SK , Chau PY , Ofloxacin eardrop treatment for active chronic suppurative otitis media: Prospective randomized study. Am J Otol 1994;15(5):670–3.

Fradis M , Brodsky A , Ben-David J , Chronic otitis media treated topically with ciprofloxacin or tobramycin. Arch Otolaryngol Head Neck Surg 1997;123(10):1057–60.

Acuin J. Chronic suppurative otitis media. Clin Evid 2004;(12):710–29.

Coates H. Chronic suppurative otitis media without cholesteatoma. In: Alper CM , Bluestone CD . eds. Advanced Therapy of Otitis Media. Hamilton, Ont.; London: B.C. Decker; 2004:299–305.

Fireman B , Black SB , Shinefield HR , Impact of the pneumococcal conjugate vaccine on otitis media. Pediatr Infect Dis J 2003;22(1):10–16.

Pichichero ME . Pathogen shifts and changing cure rates for otitis media and tonsillopharyngitis. Clin Pediatr (Phila) 2006;45(6):493–502.

Clements DA , Langdon L , Bland C , Walter E. Influenza A vaccine decreases the incidence of otitis media in 6- to 30-month-old children in day care. Arch Pediatr Adolesc Med 1995;149(10):1113–17.

Belshe RB , Mendelman PM , Treanor J , The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children. N Engl J Med 1998;338(20):1405–12.