Extramedullary plasmacytoma is a rare plasma cell neoplasm that can occur in the head and neck. In this article we describe a case of multiple synchronous extramedullary plasmacytomas involving the upper airway, pharynx, and larynx. The clinical, imaging, and pathologic features of this neoplasm are discussed, together with potential treatment options.
References
1.
BarbuRR, KhanA, PortJL, Case report: Extramedullary plasmacytoma of the larynx. Comput Med Imaging Graph1992; 16(5):359–61.
2.
KostKM. Plasmacytomas of the larynx. J Otolaryngol1990; 19(2): 141–6.
3.
BjelkenkrantzK, LundgrenJ, OlofssonJ.Extramedullary plasmacytoma of the larynx. J Otolaryngol1981; 10(1):28–34.
4.
ClampJR. Some aspects of the first recorded case of multiple myeloma. Lancet1967;2(7530):1354–6.
WillisRA. Principles of Pathology Including Bacteriology. 2nd ed. London: Butterworth & Co.; 1961:554–8.
9.
YavasO, AltundagK, SungurA.Extramedullary plasmacytoma of nasopharynx and larynx: Synchronous presentation. Am J Hematol2004;75(4):264–5.
10.
KamijoT, InagiK, NakajimaM, A case of extramedullary plasmacytoma of the larynx. Acta Otolaryngol Suppl2002;(547): 104–6.
11.
NofsingerYC, MirzaN, RowanPT, Head and neck manifestations of plasma cell neoplasms. Laryngoscope1997;107(6): 741–6.
12.
PahorAL. Plasmacytoma of the larynx. J Laryngol Otol1978; 92(3):223–32.
13.
HusainM, NguyenGK. Primary pulmonary plasmacytoma diagnosed by transthoracic needle aspiration cytology and immunocytochemistry. Acta Cytol1996;40(3):622–4.
14.
KapadiaSB, DesaiU, ChengVS. Extramedullary plasmacytoma of head and neck. A clinicopathologic study of 20 cases. Medicine (Baltimore)1982;6(5):317–29.
15.
AbemayorE, CanalisRF, GreenbergP, Plasma cell tumors of the head and neck. J Otolaryngol1988;17(7):376–81.
16.
PetrovichZ, FishkinB, HittleRE, Extramedullary plasmacytoma of the upper respiratory passages. Int J Radiat Oncol Bio Phys1977;2(7–8):723–30.
17.
BatailleR, SanyJ.Solitary myeloma: Clinical and prognostic features of a review of 114 cases. Cancer1981;48(3):845–51.
18.
WaldronJ, MitchellDB. Unusual presentations of extramedullary plasmacytoma in the head and neck. J Laryngol Otol1988; 102(1): 102–4.
19.
KnowlingMA, HarwoodAR, BergsagelDE. Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone. J Clin Oncol1983;1(4):255–62.
20.
BatsakisJG. Pathology consultation. Plasma cell tumors of the head and neck. Ann Otol Rhinol Laryngol1983;92(3 Pt 1):311–13.
21.
MediniE, RaoY, LevittSH. Solitary extramedullary plasmacytoma of the upper respiratory and digestive tracts. Cancer1980;45(11):2893–6.
22.
BoothJB, CheesmanAD, VincentiNH. Extramedullary plasmacytomata of the upper respiratory tract. Ann Otol Rhinol Laryngol1973;82(5):709–15.
23.
LohHS. A retrospective evaluation of 23 reported cases of solitary plasmacytoma of the mandible, with an additional case report. Br J Oral Maxillofac Surg1984;22(3):216–24.
24.
RubinJ, JohnsonJT, KilleenR, BarnesL.Extramedullary plasmacytoma of the thyroid associated with serum monoclonal gammopathy. Arch Otolaryngol Head Neck Surg1990;116(7):855–9.
