We describe a case of follicular dendritic cell sarcoma (FDCS) of the tonsil in a 59-year-old woman. She was successfully treated with excision of the mass and postoperative radiation therapy. According to our review of the literature, only 25 cases of extranodal FDCS in the head and neck have been previously reported, including only 10 cases that involved a tonsil. We briefly review these earlier reports, and we discuss the diagnosis and management of FDCS.
References
1.
ImalY, YamakawaM.Morphology, function, and pathology of follicular dendritic cells. Pathol Int1996;46:807–33.
2.
IdreesMT, Brandwein-GenslerM, StruachenJA, Extranodal follicular dendritic cell tumor of the tonsil: Report of a diagnostic pitfall and literature review. Arch Otolaryngol Head Neck Surg2004;130:1109–13.
3.
ChanJK, TsangWY, NgCS, Follicular dendritic cell tumors of the oral cavity. Am J Surg Pathol1994;18:148–57.
4.
NaylerSJ, VerhaartMJ, CooperK.Follicular dendritic cell tumour of the tonsil. Histopathology1996;28:89–92.
5.
Perez-OrdonezB, ErlandsonRA, RosaiJ.Follicular dendritic cell tumor: Report of 13 additional cases of a distinctive entity. Am J Surg Pathol1996;20:944–55.
6.
ChanJK, FletcherCD, NaylerSJ, CooperK.Follicular dendritic cell sarcoma. Clinicopathologic analysis of 17 cases suggesting a malignant potential higher than currently recognized. Cancer1997;79:294–313.
7.
BiddleDA, RoJY, YoonGS, Extranodal follicular dendritic cell sarcoma of the head and neck region: Three new cases, with a review of the literature. Mod Pathol2002;15:50–8.
8.
VargasH, MouzakesJ, PurdySS, Follicular dendritic cell tumor: An aggressive head and neck tumor. Am J Otolaryngol2002;23:93–8.
9.
TischM, HengstermannF, KraftK, Follicular dendritic cell sarcoma of the tonsil: Report of a rare case. Ear Nose Throat J2003;82:507–9.
10.
SatohK, HibiG, YamamotoY, Follicular dendritic cell tumor in the oro-pharyngeal region: Report of a case and a review of the literature. Oral Oncol2003;39:415–19.
11.
MondaL, WarnkeR, RosaiJ.A primary lymph node malignancy with features suggestive of dendritic reticulum cell differentiation. A report of 4 cases. Am J Pathol1986;122:562–72.
12.
Perez-OrdonezB, RosaiJ.Follicular dendritic cell tumor: Review of the entity. Semin Diagn Pathol1998;15:144–54.
13.
GerdesJ, SteinH, MasonDY, ZieglerA.Human dendritic reticulum cells of lymphoid follicles: Their antigenic profile and their identification as multinucleated giant cells. Virchows Arch B Cell Pathol Incl Mol Pathol1983;42:161–72.
14.
FonsecaR, YamakawaM, NakamuraS, Follicular dendritic cell sarcoma and interdigitating reticulum cell sarcoma: A review. Am J Hematol1998;59:161–7.
