Polymorphous low-grade adenocarcinoma (PLGA) of the parotid gland is rare. We describe a new case in which the patient underwent parotidectomy only to experience an extensive recurrence 2 years later. The recurrence was treated with radical surgical excision and radiation therapy, and the patient remained disease-free at 5 years of follow-up. We also review the literature on primary parotid PLGA.
References
1.
PeelRL. Disease of the salivary glands. In: BarnesL, ed. Surgical Pathology of the Head and Neck. 2nd ed. New York: Marcel Dekker; 2001:714–17.
MiliauskasJR. Polymorphous low-grade (terminal duct) adenocarcinoma of the parotid gland. Histopathology1991;19:555–7.
4.
PuxedduR, PuxedduP, ParodoG, FaaG.Polymorphous low-grade adenocarcinoma of the parotid gland. Eur J Morphol1998;36(suppl):262–6.
5.
GibbonsD, SaboorianMH, VuitchF, Fine-needle aspiration findings in patients with polymorphous low grade adenocarcinoma of the salivary glands. Cancer1999;87:31–6.
6.
VincentSD, HammondHL, FinkelsteinMW. Clinical and therapeutic features of polymorphous low-grade adenocarcinoma. Oral Surg Oral Med Oral Pathol1994;77:41–7.
7.
CastleJT, ThompsonLD, FrommeltRA, Polymorphous low grade adenocarcinoma: A clinicopathologic study of 164 cases. Cancer1999;86:207–19.
8.
KempBL, BatsakisJG, el-NaggarAK, Terminal duct adenocarcinomas of the parotid gland. J Laryngol Otol1995;109:466–8.
GneppDR, ChenJC, WarrenC.Polymorphous low-grade adenocarcinoma of minor salivary gland. An immunohistochemical and clinicopathologic study. Am J Surg Pathol1988;12:461–8.
