Leiomyosarcoma is a malignant smooth-muscle tumor that has a predilection for the gastrointestinal tract and the female genital tract. It is locally fast-spreading and highly aggressive, and the prognosis is poor. We report two cases of leiomyosarcoma of the maxilla in patients who sought treatment for maxillary swelling, nasal obstruction, and epistaxis; one patient also had orbital involvement and cervical lymph node metastasis. Both patients underwent radical surgery followed by chemo-and/or radiotherapy. The patient with orbital involvement died shortly thereafter, but the other was disease-free at 18 months.
OrtegaJ.M., Gomez-AnguloJ.C., AragonesP.[Leiomyosarcoma of the paranasal sinuses with intracranial involvement: Report of a clinical case and review of the literature]. Neurocirugia (Astur)2001; 12: 331–7.
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TanakaH., WestessonP.L., WilburD.C.Leiomyosarcoma of the maxillary sinus: CT and MRI findings. Br J Radiol1998; 71: 221–4.
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CarranR.L., MyersE.N.Neoplasms of the nose and paranasal sinuses. In: BaileyB.J., ed. Head and Neck Surgery: Otolaryngology. 2nd ed. Vol. 2. Philadelphia: Lippincott-Raven, 1998: 1450.
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RiceD.H., StanleyR.B.Surgical therapy of tumors of the nasal cavity, ethmoid sinus and maxillary sinus. In: ThawleyS.E., PanjeW.R., eds. Comprehensive Management of Head and Neck Tumors. 2nd ed. Vol. 1. Philadelphia: W.B. Saunders, 1999: 571.
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SumidaT., HamakawaH., OtsukaK., TaniokaH.Leiomyosarcoma of the maxillary sinus with cervical lymph node metastasis. J Oral Maxillofac Surg2001; 59: 568–71.
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IzumiK., MaedaT., ChengJ., SakuT.Primary leiomyosarcoma of the maxilla with regional lymph node metastasis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod1995; 80: 310–19.
