Parathyroid carcinoma is a rare malignancy, and experience with its management is limited. It is generally accepted that surgery is the treatment of choice, and the initial operative intervention might represent the only chance for long-term success. At the time of surgery, a high index of suspicion for carcinoma is vital to performing the appropriate surgical procedures, because frozen-section diagnosis of parathyroid carcinoma is notoriously unreliable. In this article, we describe our experience with this rare entity.
References
1.
FujimotoY, ObaraT, ItoY, Localization and surgical resection of metastatic parathyroid carcinoma. World J Surg1986;10:539–47.
2.
SandelinK, AuerG, BondesonL, Prognostic factors in parathyroid cancer: A review of 95 cases. World J Surg1992;16:724–31.
3.
BondesonL, SandelinK, GrimeliusL.Histopathological variables and DNA cytometry in parathyroid carcinoma. Am J Surg Pathol1993;17:820–9.
4.
FujimotoY, ObaraT, ItoY, Surgical treatment of ten cases of parathyroid carcinoma: Importance of an initial en bloc tumor resection. World J Surg1984;8:392–400.
5.
HolmesEC, MortonDL, KetchamAS. Parathyroid carcinoma: A collective review. Ann Surg1969;169:631–40.
6.
LevinKE, GalanteM, ClarkOH. Parathyroid carcinoma versus parathyroid adenoma in patients with profound hypercalcemia. Surgery1987;101:649–60.
7.
SchantzA, CastlemanB.Parathyroid carcinoma. A study of 70 cases. Cancer1973;31:600–5.
8.
CastlemanB.Tumors of the parathyroid glands. In: Atlas of Tumor Pathology. Washington, D.C.: Armed Forces Institute of Pathology, 1952:50–4.
9.
DeLellisR.Tumors of the parathyroid glands. In: Atlas of Tumor Pathology. 3rd series, fascicle 6. Washington, D.C.: Armed Forces Institute of Pathology, 1993:53–63.
10.
WangCA, GazRD. Natural history of parathyroid carcinoma. Diagnosis, treatment, and results. Am J Surg1985;149:522–7.
11.
FlyeMW, BrennanMF. Surgical resection of metastatic parathyroid carcinoma. Ann Surg1981;193:425–35.
