Basaloid squamous cell carcinoma is a variant of squamous cell carcinoma. This malignancy has a predilection for the upper aerodigestive tract, although it has been found in multiple other sites. The tumor is highly aggressive biologically, and the overall prognosis is poor despite intensive treatment. We describe a case of basaloid squamous cell carcinoma of the larynx that metastasized to the spine.
References
1.
FerlitoA, AltavillaG, RinaldoA, DoglioniC.Basaloid squamous cell carcinoma of the larynx and hypopharynx. Ann Otol Rhinol Laryngol1997;106:1024–35.
2.
MoriceWG, FerreiroJA. Distinction of basaloid squamous cell carcinoma from adenoid cystic and small cell undifferentiated carcinoma by immunohistochemistry. Hum Pathol1998;29:609–12.
3.
BarnesL, FerlitoA, AltavillaG, Basaloid squamous cell carcinoma of the head and neck: Clinicopathological features and differential diagnosis. Ann Otol Rhinol Laryngol1996;105:75–82.
4.
WainSL, KierR, VollmerRT, BossenEH. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: Report of 10 cases. Hum Pathol1986;17:1158–66.
5.
SchwartzRM. Pathology of laryngeal tumors. In: ThawleySE, PanjeWR, BatsakisJG, LindbergRD, eds. Comprehensive Management of Head and Neck Tumors. 2nd ed., vol. 2. Philadelphia: W.B. Saunders, 1999:959–60.
