This article presents the results of a noncontrolled clinical study of 20 persons with Leber's hereditary optic neuropathy who were treated from 1976 to 1990 at the Low Vision Centre, Finnish Federation of the Visually Handicapped. It emphasizes the importance of early functional visual rehabilitation and the use of low vision aids to help patients perform their daily activities.
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References
1.
BallantyneA.J., and MichaelsonI.C. (1973). Textbook of the fundus of the eye.London: Churchill Livingstone.
2.
BeckerS.L., and NowakowskiR.W. (1985). Leber optic atrophy: Low vision case report.American Journal of Optometry and Physiological Optics, 65, 209–211.
3.
BellJ. (1931). Hereditary optic atrophy.London: Cambridge University Press.
4.
JohnsD.R., HeherK.L., MillerN.R., and SmithK.L. (1993). Leber's hereditary optic neuropathy: Clinical manifestations of the 14484 mutation.Archives of Ophthalmology, 111, 495–498.
5.
JohnsD.R., SmithK.H., and MillerN.R. (1992). Leber's hereditary optic neuropathy: Clinical manifestations of the 3460 mutation.Archives of Ophthalmology, 110, 1577–1581.
6.
JohnsD.R., SmithK.H., SavinoP.J., and MillerN.R. (1993). Leber's hereditary optic neuropathy: Clinical manifestations of the 15257 mutation.Ophthalmology, 100, 981–986.
7.
MillerN.R. (1982). Walsh and Hoyt's clinical neuro-ophthalmology.Baltimore, MD: Williams & Wilkins.
8.
NewmanN.J., LottM.T., and WallaceD.C. (1991). The clinical characteristics of pedigrees of Leber's hereditary optic neuropathy with the 11778 mutation.American Journal of Ophthalmology, 111, 750–762.
StoneE.M., NewmanN.J., MillerN.R., JohnsD.R., LottM.T., and WallaceD.C. (1992). Visual recovery in patients with Leber's hereditary optic neuropathy and the 11778 mutation.Journal of Clinical Neuro-Ophthalmology, 12, 10–14.
11.
World Health Organization (WHO). (1967). Manual of the international statistical classification of diseases, injuries, and causes of death.Geneva: Author.
