Using a set of psychophysical tests, we compared the olfactory abilities of 8 persons who became blind early in life and 16 sighted persons in a control group who were matched for age, sex, and handedness. The results indicated that those who became blind early in life developed compensatory perceptual mechanisms in the olfactory domain that involve basic sensory processes, such as the detection of odors.
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References
1.
AmediA., FloelA., KnechtS., ZoharyE., & CohenL. G. (2004). Transcranial magnetic stimulation of the occipital pole interferes with verbal processing in blind subjects. Nature Neuroscience, 7, 1266–1270.
2.
AmediA., RazN., PiankaP., MalachR., & ZoharyE. (2003). Early visual cortex activation correlates with superior verbal memory performance in the blind. Nature Neuroscience, 6, 758–766.
3.
BavelierD., & NevilleH. J. (2002). Cross-modal plasticity: Where and how?Nature Reviews Neurosciences, 3, 443–452.
4.
BlissI., KujalaT., & HämäläinenH. (2004). Comparison of blind and sighted participants’ performance in a letter recognition working memory task. Cognitive Brain Research, 18, 273–277.
5.
BrämersonA., JohanssonL., EkL., NordinS., & BendeM. (2004). Prevalence of olfactory dysfunction: The Skövde Population-Based Study. The Laryngoscope, 114, 733–737.
6.
BüchelC., PriceC., FrackowiakR. S. J., & FristonK. (1998). Different activation patterns in the visual cortex of late and congenitally blind subjects. Brain, 121, 409–419.
7.
BurtonH. (2003). Visual cortex activity in early and late blind people. Journal of Neuroscience, 23, 4005–4011.
8.
BurtonH., & Mc LarenD. G. (2008). Visual deprivation effects on somatosensory and visual systems: Behavioral and cortical changes. In BasbaumA. I., KanekoA., ShepherdG. M., & WestheimerG. (Eds.), The senses: A comprehensive reference (Vol. 6, pp. 363–392). San Diego, CA: Academic Press.
9.
BurtonH., SnyderA. Z., ConturoT. E., AkbudakE., OllingerJ. M., & RaichleM. E. (2002). Adaptive changes in early and late blind: A fMRI study of braille reading. Journal of Neurophysiology, 87, 589–607.
CollignonO., RenierL., BruyerR., TranduyD., & VeraartC. (2006). Improved selective and divided spatial attention in early blind subjects. Brain Research, 1075, 175–182.
12.
CuevasI., PlazaP., RombauxP., De VolderA. G., & RenierL. (2009). Odour discrimination and identification are improved in early blindness. Neuropsychologia, 47, 3079–3083.
13.
DiekmannH., WalgerM., & Von WedelH. (1994). Sense of smell in deaf and blind patients. HNO, 42, 264–269.
14.
FerdenziC., HolleyA., & SchaalB. (2004). Impacts de la déficience visuelle sur le traitement des odeurs [Impact of visual impairment on odor processing]. Voir, 28–29, 126–143.
15.
UgoldreichD., & KanicsI. (2003). Tactile acuity is enhanced in blindness. Journal of Neuroscience, 23, 3439–3445.
16.
GoldreichD., & KanicsI. (2006). Performance of blind and sighted humans on a tactile grating detection task. Perception & Psychophysics, 68, 1363–1371.
17.
GougouxF., LeporeF., LassondeM., VossP., ZatorreR. J., & BelinP. (2004, July 15). Neuropsychology: Pitch discrimination in the early blind. Nature, 430, 309.
18.
GougouxF., ZatorreR. J., LassondeM., VossP., & LeporeF. (2005). A functional neuroimaging study of sound localization: Visual cortex activity predicts performance in early-blind individuals. PLoS Biology3(2), e27, 324–333.
19.
GrantA. C., ThiagarajahM. C., & SathianK. (2000). Tactile perception in blind braille readers: A psychophysical study of acuity and hyperacuity using gratings and dot patterns. Perception & Psychophysics, 62, 301–312.
20.
HatwellI. (2003). Psychologie cognitive de la cécité précoce [Cognitive psychology of early blindness].Paris: Dunod.
21.
HeilmannS., StrehleG., RosenheimK., DammM., & HummelT. (2002). Clinical assessment of retronasal olfactory function. Archives of Otolaryngology: Head & Neck Surgery, 128, 414–418.
22.
HellerM. A. (1991). Haptic perception in blind people. In HellerM.A., & SchiffW. (Eds.), The psychology of touch (pp. 239–262). Hillsdale, NJ: Lawrence Erlbaum.
23.
HummelT., KobalG., GudziolH., & Mackay-SimA. (2007). Normative data for the Sniffin’ Sticks including tests of odor identification, odor discrimination, and olfactory thresholds: An upgrade based on a group of more than 3,000 subjects. European Archives of Otorhinolaryngology, 264, 237–243.
24.
HummelT., & NordinS. (2005). Olfactory disorders and their consequences for quality of life. Acta Oto-Laryngologica, 125, 116–121.
25.
HummelT., SekingerB., WolfS. R., PauliE., & KobalG. (1997). Sniffin’ Sticks: Olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chemical Senses, 22, 39–52.
26.
KobalG., KlimekL., WolfensbergerM., GudziolH., TemmelA., OwenC. M., SeeberH., PauliE., & HummelT. (2000). Multicenter investigation of 1,036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds. European Archives of Otorhinolaryngology, 257, 205–211.
27.
LandisB. N., KonnerthC. G., & HummelT. (2004). A study on the frequency of olfactory dysfunction. The Laryngoscope, 114, 1764–1769.
28.
LessardN., PareM., LeporeF., & LassondeM. (1998). Early-blind human subjects localize sound sources better than sighted subjects. Nature, 395(6699), 278–280.
29.
LewaldJ. (2002). Vertical sound localization in blind humans. Neuropsychologia40, 1868–1872.
30.
MerabetL. B., HamiltonR., SchlaugG., SwisherJ. D., KiriakopoulosE. T., PitskelN. B., KauffmanT., & Pascual-LeoneA. (2008). Rapid and reversible recruitment of early visual cortex for touch. PLoS One, 3(8), e3046.
31.
MurphyC., & CainW. S. (1986). Odor identification: The blind are better. Physiology & Behavior, 37, 177–180.
32.
Pascual-LeoneA., AmediA., FregniF., & MerabetL. B. (2005). The plastic human brain cortex. Annual Review of Neuroscience, 28, 377–401.
33.
Pascual-LeoneA., & HamiltonR. (2001). The metamodal organization of the brain. Progress in Brain Research, 134, 427–445.
34.
PurdonS. E., KleinS., & Flor-HenryP. (2001). Menstrual effects on asymmetrical olfactory acuity. Journal of the International Neuropsychological Society, 7, 703–709.
35.
RöderB., & RöslerF. (2003). Memory for environmental sounds in sighted, congenitally blind and late blind adults: Evidence for cross-modal compensation. International Journal of Psychophysiology, 50(1-2), 27–39.
36.
RöderB., RöslerF., & NevilleH. J. (2000). Event-related potentials during language processing in congenitally blind and sighted people. Neuropsychologia, 38, 1482–1502.
37.
RöderB., Teder-SälejärviW., SterrA., RöslerF., HillyardS. A., & NevilleH. J. (1999). Improved auditory spatial tuning in blind humans. Nature, 400, 162–166.
38.
RosenbluthR., GrossmanE., & KaitzM. (2000). Performance of early-blind and sighted children on olfactory tasks. Perception, 29, 101–110.
39.
SadatoN., OkadaT., HondaM., & YonekuraY. (2002). Critical period for cross-modal plasticity in blind humans: A functional MRI study. Neuroimage, 16, 389–400.
40.
SchwennO., HundorfI., MollB., PitzS., & MannW. J. (2002). Do blind persons have a better sense of smell than normal sighted people?Klinische Monatsblätter für Augenheilkunde, 219, 649–654.
41.
SmithR. S., DotyR. L., BurlingameG. K., & McKeownD. A. (1993). Smell and taste function in the visually impaired. Perception & Psychophysics, 54, 649–655.
42.
StevensA. A., & WeaverK. (2005). Auditory perceptual consolidation in early-onset blindness. Neuropsychologia, 43, 1901–1910.
43.
Van BovenR. W., HamiltonR. H., KauffmanT., KeenanJ. P., & Pascual-LeoneA. (2000). Tactile spatial resolution in blind Braille readers. Neurology, 54, 2230–2236.
44.
VossP., LassondeM., GougouxF., FortinM., GuillemotJ. P., & LeporeF. (2004). Early- and late-onset blind individuals show supra-normal auditory abilities in far-space. Current Biology14, 1734–1738.
45.
WakefieldC. E., HomewoodJ., & TaylorA. J. (2004). Cognitive compensations for blindness in children: An investigation using odour naming. Perception, 33, 429–442.
46.
WatanabeK., UmezuK., & KurahashiT. (2002). Human olfactory contrast changes during the menstrual cycle. Japanese Journal of Physiology, 52, 353–359.
47.
WeeksR., HorwitzB., Aziz-SultanA., TianB., WessingerC. M., CohenL. G., HallettM., & RauscheckerJ. P. (2000). A positron emission tomography study of auditory localization in the congenitally blind. Journal of Neuroscience, 20, 2664–2672.
48.
WieselT. N. (1982). Postnatal development of the visual cortex and the influence of environment. Nature, 299(5884), 583–591.
49.
ZwiersM. P., Van OpstalA. J., & CruysbergJ. R. M. (2001). A spatial hearing deficit in early-blind humans. Journal of Neuroscience, 21, 142–145.
