Charles Bonnet syndrome (CBS) commonly occurs in older adults with visual impairments, particularly those with age-related macular degeneration. It is characterized by complex visual hallucinations in individuals without mental disorders. The authors explore diagnostic criteria, demographic characteristics, clinical features, theories of pathogenesis, and management options for people who are diagnosed with CBS.
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References
1.
AbbotE. J., ConnorG. B., ArtesP. H., & AbadiR. V. (2007). Visual loss and visual hallucinations in patients with age-related macular degeneration (Charles Bonnet syndrome). Investigative Ophthalmology & Visual Science, 48, 1416–1423.
BarnesJ., & DavidA. S. (2001). Visual hallucinations in Parkinson's disease: A review and phenomenological survey. Journal of Neurology, Neurosurgery, and Psychiatry, 70, 727–747.
4.
BatraA., BartelsM., & WormstallH. (1997). Therapeutic options in Charles Bonnet syndrome. Acta Psychiatrica Scandinavica, 96, 129–133.
5.
BeckJ., & HarrisJ. (1994). Visual hallucinations in non-delusional elderly. International Journal of Geriatric Psychiatry, 9, 531–536.
6.
BerriosG. E., & BrookP. (1984). Visual hallucinations and sensory delusions in the elderly. British Journal of Psychiatry, 144, 662–664.
7.
BurkeW. (2005). The neural basis of Charles Bonnet hallucinations: A hypothesis. Journal of Neurology and Psychiatry, 73, 535–541.
8.
CohenS. Y., BulikA., TadayoniR., & QuentelG. (2003). Visual hallucinations and Charles Bonnet syndrome after photo-dynamic therapy for age related macular degeneration. British Journal of Ophthalmology, 87, 977–979.
9.
CollertonD., PerryE., & McKeithI. (2005). Why people see things that are not there: A novel perception and attention deficit model for recurrent complex visual hallucinations. Behavioral and Brain Sciences, 28, 737–794.
10.
CrumblissK. E., TaussigM. J., & JayW. M. (2008). Vision rehabilitation and Charles Bonnet syndrome. Seminars in Ophthalmology, 23, 121–126.
11.
ElbersN., GeraertsE., & van HeerdenJ. (2007). Hallucinating consistency. Theory & Psychology, 17, 587–602.
12.
FernandezA., LichtsheinG., ViewegW., & VictorR. (1997). The Charles Bonnet syndrome: A review. Journal of Nervous and Mental Disease, 185, 195–200.
13.
ffytcheD. H., HowardR. J., BrammerM. J., DavidA., WoodruffP., & WilliamsS. (1998). The anatomy of conscious vision: An fMRI study of visual hallucinations. Nature Neuroscience, 1, 738–742.
14.
GoldK., & RabinsR. V. (1989). Isolated visual hallucinations and the Charles Bonnet syndrome: A review of the literature and presentation of six cases. Comprehensive Psychiatry, 30, 90–98.
15.
HedgesT. R. (2007). Charles Bonnet, his life, and his syndrome. Survey of ophthalmology, 52, 111–114.
16.
HolroydS., RabinsP. V., FinkelsteinD., & LavrishaM. (1994). Visual hallucinations in patients from an ophthalmology clinic and medical clinic population. Journal of Nervous and Mental Disease, 182, 273–276.
17.
HolroydS., RabinsP. V., FinkelsteinD., NicholsonM. C., ChaseG. A., & WisniewskiS. C. (1992). Visual hallucinations in patients with macular degeneration. American Journal of Psychiatry, 149, 1701–1706.
18.
HolroydS., & RabinsP. V. (1996). A three-year follow-up study of visual hallucinations in patients with macular degeneration. Journal of Nervous and Mental Disease, 184, 188–189.
19.
JacksonM. L., BassettK., NirmalanP. V., & SayreE. C. (2007). Contrast sensitivity and visual hallucinations in patients referred to a low vision rehabilitation clinic. British Journal of Ophtahlmology, 91, 296–298.
20.
KahnJ. C., ShahidH., ThurlbyD. A., YatesJ. R., & MooreA. T. (2008). Charles Bonnet syndrome in age-related macular degeneration: The nature and frequency of images in subjects with end-stage disease. Ophthalmic Epidemiology, 15, 202–208.
21.
KitayamaM., Wada-IsoeK., NakasoK., IrizawaY., & NakashimaK. (2007). Clinical evaluation of Parkinson's disease dementia: Association with aging and visual hallucinations. Acta Neurologica Scandinavica, 116, 190–195.
22.
LangU. E., StogowskiD., SchulzeD., DomulaM., SchmidtE., GallinatJ., TugtekinS. M., & FelberW. (2007). Charles Bonnet syndrome: Successful treatment of visual hallucinations due to vision loss with selective serotonin re-uptake inhibitors. Journal of Psychopharmacology, 21, 553–555.
23.
LannonS. P., StevensonM. R., WhiteS. T., LoganJ. F., Reinhardt-RutlandA. H., & JacksonA. J. (2006). Visual hallucinations in patients with age-related macular degeneration (AMD). Visual Impairment Research, 8(1-2), 9–16.
24.
MatsuiH., UdakaF., TamuraA., OdaM., KuboriT., NishinakaK., & KameyamaM. (2006). Impaired visual acuity as a risk factor for visual hallucinations in Parkinson's disease. Journal of Geriatric Psychiatry and Neurology, 19, 36–40.
25.
MenonG. J., RahmanI., MenonS. J., & DuttonG. N. (2003). Complex visual hallucinations in the visually impaired: The Charles Bonnet syndrome. Survey of Ophthalmology, 48, 58–72.
26.
MerabetL. B., MaguireD., WardeA., AlterescuK., StickgoldR., & Pascual-LeoneA. (2004). Visual hallucinations during prolonged blindfolding in sighted subjects. Journal of Neuro-Ophthalmology, 24, 109–113.
27.
MocellinR., WalterfangM., & VelakoulisD. (2006). Neuropsychiatry of complex visual hallucinations. Australian and New Zealand Journal of Psychiatry, 40, 742–751.
28.
MosimannU. P., CollertonD., DudleyR., MeyerT. D., GrahamG., DeanJ. L. (2008). A semi-structured interview to assess visual hallucinations in older people. International Journal of Geriatric Psychiatry, 23, 712–718.
29.
NadarajahJ. (1998). Visual hallucinations and macular degeneration: An example of the Charles Bonnet Syndrome. Australian and New Zealand Journal of Ophthalmology, 26, 63–65.
30.
NesherR., NesherG., EpsteinE., & AssiaE. (2001). Charles Bonnet syndrome in glaucoma patients with low vision. Journal of Glaucoma, 10, 396–400.
31.
PliskinN. H., KiolbasaT. A., TowleV. L., PankowL., ErnestJ. T., NoronhaA., & LuchinsD. J. (1996). Charles Bonnet syndrome: An early marker for dementia?Journal of the American Geriatrics Society, 44, 1055–1061.
32.
RabinsP. (1994). The genesis of phantom (deenervation) hallucinations: An hypothesis. International Journal of Geriatric Psychiatry, 9, 775–777.
33.
RovnerB. W. (2002). The Charles Bonnet syndrome: Visual hallucinations caused by vision impairment. The Psychiatric Consultant, 57(6), 45–46.
34.
SanthouseA. M., HowardR. J., & ffytcheD. H. (2000). Visual hallucinatory syndromes and the anatomy of the visual brain. Brain, 123, 2055–2064.
35.
SchultzG., & MelzackR. (1991). The Charles Bonnet syndrome: “Phantom images.”Perception, 20, 809–825.
36.
ScottI. U., ScheinO. D., FeuerW. J., & FolsteinM. F. (2001). Visual hallucinations in patients with retinal disease. American Journal of Ophthalmology, 131, 590–598.
37.
ShiraishiY., TeraoT., IbiK., NakamuraJ., & TawaraA. (2004). The rarity of Charles Bonnet syndrome. Journal of Psychiatric Research, 38, 207–213.
38.
TanC. S. H., LimV. S. Y., HoD. Y. M., YeoE., NgB. Y., & Au EongK. G. (2004). Charles Bonnet syndrome in Asian patients in a tertiary ophthalmic centre. British Journal of Ophthalmology, 88, 1325–1329.
39.
TeraoT. (2002). The present state of Charles Bonnet syndrome. Psychogeriatrics, 2, 6–14.
40.
TeunisseR. J., CruysbergJ. R., HoefnagelsW. H., KuinY., VerbeekA. L., & ZitmanF. G. (1999). Social and psychological characteristics of elderly visually handicapped patients with the Charles Bonnet syndrome. Comprehensive Psychiatry, 40, 315–319.
41.
TeunisseR. J., CruysbergJ. R. M., VerbeekA., & ZitmanF. G. (1995). The Charles Bonnet syndrome: A large prospective study in the Netherlands. British Journal of Psychiatry, 166, 254–257.
42.
TeunisseR. J., ZitmanF. G., CruysbergJ. R. M., HoefnagelsW. H. L., & VerbeekA. L. M. (1996). Visual hallucinations in psychologically normal people: Charles Bonnet's syndrome. The Lancet, 347, 794–797.
43.
TeunisseR. J., ZitmanF. G., & RaesD. C. (1994). Clinical evaluation of 14 patients with Charles Bonnet syndrome (isolated visual hallucinations). Comprehensive Psychiatry, 35, 70–75.