Is there a Role for Surgery in Small-Cell Lung Cancer?

Ihde DC . Chemotherapy of lung cancer. N Engl J Med 1992; 327: 1434–41.

Mountain CF . Clinical biology of small cell carcinoma: relationship to surgical therapy. Semin Oncol 1978; 5: 272–9.

Takita H , Brugarolas A , Marabella P. Small cell carcinoma of the lung: clinicopathologic studies. J Thorac Cardiovasc Surg 1973; 66: 472–7.

Fox W , Scadding JG . Medical Research Council comparative trial of surgery and radiotherapy for primary treatment of small-celled or oat-celled carcinoma of the bronchus: ten-year follow-up. Lancet 1973; ii: 63–5.

Working-Party on the Evaluation of Different Methods of Therapy in Carcinoma of the Bronchus. Comparative trial of surgery and radiotherapy for the primary treatment of small-celled, or oat-celled carcinoma of the bronchus. Lancet 1966;ii: 979–86.

Green RA , Humphrey E , Close H. Alkylating agents in bronchogenic carcinoma. Am J Med 1969; 46: 516–25.

Medical Research Council Lung Cancer Working Party. Radiotherapy alone or with chemotherapy in the treatment of small-cell carcinoma of the lung. Br J Cancer 1979; 40: 1–10.

Uhde DC . Small cell lung cancer: State-of-the-art therapy 1994. Chest 1995; 107: 243S–8S.

Wittes RE . Small-cell lung cancer: an overview of issues in therapy. Sem Surg Oncol 1993; 9: 127–34.

Ichinose Y , Hara N , Ohta M. Comparison between resected and irradiated small cell lung cancer in patients in stages I through IIIa. Ann Thorac Surg 1992; 53: 95–100.

Macchiarini P , Hardin M , Basolo F. Surgery plus adjuvant chemotherapy for T1-3N0M0 small-cell lung cancer. Rationale for current approach. Am J Clin Oncol 1991; 14: 218–24.

Shepherd FA , Ginsberg RJ , Feld R. Surgical treatment for limited small-cell lung cancer. The University of Toronto Lung Oncology Group experience. J Thorac Cardiovasc Surg 1991; 101: 385–93.

Higgins GA , Shields TW , Keehn RJ . The solitary pulmonary nodule: ten-year follow-up of Veterans Administration-Armed Forces Cooperative Study. Arch Surg 1975; 110: 570–5.

Kreisman H , Wolkove N , Quoix E. Small cell lung cancer presenting as a solitary pulmonary nodule. Chest 1992; 101: 225–31.

Quoix E , Fraser R , Wolkove N. Small cell lung cancer presenting as a solitary pulmonary nodule. Cancer 1990; 66: 577–82.

Shields TW , Higgins GA , Matthews MG . Surgical resection in the management of small cell carcinoma of the lung. J Thorac Cardiovasc Surg 1982; 84: 481–8.

Gephardt GN , Grady KJ , Ahmad M. Peripheral small cell undifferentiated carcinoma of the lung: clinicopathologic features of 17 cases. Cancer 1988; 61: 1002–8.

Urschel JD . Pretreatment natural history of small cell lung cancer presenting as a solitary pulmonary nodule. J Cardiovasc Surg 1994; 35: 273–5.

Muhm JR , Miller WE , Fontana RS . Lung cancer detected during a screening program using four-month radiographs. Radiology 1983; 148: 609–15.

Kron IL , Harman PK , Mills SE . A reappraisal of limited stage undifferentiated carcinoma of the lung. Does stage I small cell undifferentiated carcinoma exist? J Thorac Cardiovasc Surg 1982; 84: 734–7.

Warren WH , Faber LP , Gould VE . Neuroendocrine neoplasms of the lung. A clinicopathologic update. J Thorac Cardiovasc Surg 1989; 98: 321–32.

Deneffe G , Lacquet LM , Verbeken E. Surgical treatment of bronchogenic carcinoma: a retrospective study of 720 thoracotomies. Ann Thorac Surg 1988; 45: 380–3.

Shah SS , Thompson J , Goldstraw P. Results of operation without adjuvant therapy in treatment of small cell lung cancer. Ann Thorac Surg 1992; 54: 498–501.

Shore DF , Paneth M. Survival after resection of small cell lung cancer of the bronchus. Thorax 1980; 35: 819–22.

Urschel JD . Surgical treatment of peripheral small cell lung cancer. Chest Surg Clin N Am 1997; 7: 95–103.

Friess GG , McCracken JD , Troxell ML . Effect of initial resection of small-cell carcinoma of the lung: a review of Southwest Oncology Group study 7628. J Clin Oncol 1985; 3: 964–8.

Shepherd FA , Ginsberg RJ , Evans WK . Reduction in local recurrence and improved survival in surgically treated patients with small-cell lung cancer. J Thorac Cardiovasc Surg 1983; 86: 498–506.

Shepherd FA . Surgical management of small cell lung cancer. In: Pass HI , Mitchell JB , Johnson DH , Turrisi AT eds. Lung Cancer: Principles and Practice. Philadelphia: Lippincott-Raven, 1996: 899.

Ginsberg RJ . Surgery for small cell lung cancer. Lung Cancer 1993; 9: 275–80.

Shields TW . Surgery for small-cell lung cancer. In: Roth JA , Cox JD , Hong WK eds. Lung Cancer. Boston: Blackwell Scientific, 1993: 168.

Davis S , Crino L , Tonato M. A prospective analysis of chemotherapy following surgical resection of clinical stage I–II small-cell lung cancer. Am J Clin Oncol 1993; 16: 93–5.

Hara N , Ichinose Y , Kuda T. Long-term survivors in resected and nonresected small cell lung cancer. Oncology 1991; 48: 441–7.

Hayata Y , Funatsu H , Suemasu K. Surgical indications in small cell carcinoma of the lung. Jap J Clin Oncol 1978; 8: 93–100.

Karrer K , Denck H , Karnicka-Mlodkowska H. The importance of surgery as the first step in multimodality treatment of small cell bronchial carcinoma. The ISC Lung Cancer Study Group. Int J Clin Pharmacol Res 1990; 10: 257–63.

Maassen W , Greschuchna D. Small cell carcinoma of the lung: to operate or not? Surgical experience and results. Thorac Cardiovasc Surg 1986; 34: 71–6.

Shepherd FA , Evans WK , Feld R. Adjuvant chemotherapy following surgical resection for small-cell carcinoma of the lung. J Clin Oncol 1988; 6: 832–8.

Pignon JP , Arriagada R , Ihde DC . A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med 1992; 327: 1618–24.

Warde P , Payne D. Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A metaanalysis. J Clin Oncol 1992; 10: 890–5.

Shepherd FA . The role of chemotherapy in the treatment of small cell lung cancer. Chest Surg Clin N Am 1997; 7: 113–33.

Elliott JA , Osterlind K , Hirsch FR . Metastatic patterns in small-cell lung cancer: correlation of autopsy findings with clinical parameters in 537 patients. J Clin Oncol 1987; 5: 246–54.

Shepherd FA , Ginsberg RJ , Patterson GA . A prospective study of adjuvant surgical resection after chemotherapy for limited small cell lung cancer. J Thorac Cardiovasc Surg 1989; 97: 177–86.

Prager RL , Foster JM , Hainsworth JD . The feasibility of adjuvant surgery in limited-stage small cell carcinoma: a prospective evaluation. Ann Thorac Surg 1984; 38: 622–6.

Williams CJ , McMillan I , Lea R. Surgery after initial chemotherapy for localized small cell carcinoma of the lung. J Clin Oncol 1987; 5: 1579–88.

Johnson DH , Einhorn LH , Mandelbaum I. Post chemotherapy resection of residual tumour in limited stage small cell lung cancer. Chest 1987; 92: 241–6.

Baker RR , Ettinger DS , Ruckdeschel JD . The role of surgery in the management of selected patients with small-cell carcinoma of the lung. J Clin Oncol 1987; 5: 697–702.

Benfield GF , Matthews HR , Watson DC . Chemotherapy plus adjuvant surgery for local small cell lung cancer. Eur J Surg Oncol 1989; 15: 341–4.

Zatopek NK , Holoye PY , Ellerbroek NA . Resectability of small-cell lung cancer following induction chemotherapy in patients with limited disease (stage II–IIIb). Am J Clin Oncol 1991; 14: 427–32.

Hara N , Ohta M , Ichinose Y. Influence of surgical resection before and after chemotherapy on survival in small cell lung cancer. J Surg Oncol 1991; 47: 53–61.

Shepherd FA , Ginsberg RJ , Haddad R. Importance of clinical staging in limited small-cell lung cancer: a valuable system to separate prognostic subgroups. J Clin Oncol 1993; 11: 1592–7.

Lad T , Piantadosi S , Thomas P. A prospective randomized trial to determine the benefit of surgical resection of residual disease following response of small cell lung cancer to combination chemotherapy. Chest 1994; 106: 320S-3S.

Shepherd FA , Ginsberg R , Patterson GA . Is there ever a role for salvage operations in limited small-cell lung cancer? J Thorac Cardiovasc Surg 1991; 101: 196–200.

Yamada K , Saijo N , Kojima A. A retrospective analysis of patients receiving surgery after chemotherapy for small cell lung cancer. Jap J Clin Oncol 1991; 21: 39–45.

Mangum MD , Greco FA , Hainsworth JD . Combined small-cell and non-small-cell lung cancer. J Clin Oncol 1989; 7: 607–12.