The Contribution of Clinical Genetics to Molecular Genetics in Psychiatry

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Winokur G . Mania and Depression, a Classification of Syndrome and Disease. Baltimore and London: The Johns Hopkins University Press, 1991.

Winokur G Tsuang M Crowe R . The Iowa 500: Affective disorders in relatives of manic and depressed patients. Am J Psychiatry 1982;139:209–12.

Winokur G . A familial (Genetic) methodology for determining valid types of affective illnesses. Pharmacopsychiatry 1992;25:14–17.

Winokur G Coryell W . Familial alcoholism and primary unipolar major depressive disorder. Am J Psychiatry 1991;148:184–8.

Wilson A Elston R Mallott D Tran L Winokur G . The current status of genetic linkage studies of alcoholism and unipolar depression. Psychiat Gene 1991;2:107–24.

Wang Z Crowe R Tanna V Winokur G . Alpha-2 adrenergic receptor subtypes in depression: A candidate gene study. J Affect Disord 1992;25:191–6.

Schuckit M Rimmer J Reich T Winokur G . Alcoholism: Antisocial traits in male alcoholics. Br J Psychiatry 1970;117:575–6.

Cloninger C Bohman M Sigvardsson S . Inheritance of alcohol abuse: Crossfostering analysis of adopted men. Arch Gen Psychiatry 1981;38:861–8.

Von Knorring A-L Hallman J Von Knorring L Oreland L . Platelet monoamine oxidase activity in Type 1 and Type 2 alcoholism. Alcohol Alcoholism 1991;26:409–16.

Tsuang M Winokur G Crowe R . Morbidity risks of schizophrenic and affective disorders among first-degree relatives of patients with schizophrenia, mania, depression and surgical controls. Br J Psychiatry 1980;137:497–504.

Winokur G Clayton P Reich T . Manic depressive illness. St Louis, USA: Mosby Co., 1969.

Gill M McKeon P Humphries P . Linkage analysis of manic depression in an Irish family using H-rasI and INS DNA markers. J Med Genet 1988;25:634–7.

Hoehe M Goldin L Baetge E Lentes K-U Berrettini W . The alpha-2 adrenoreceptor vulnerability hypothesis of depression: From the clonidine growth hormone stimulation test to the genes including a human alpha-2 adrenoreceptor and phenylethanolamine in methyl transferase. In: Bunney W Hippius H Laakman G Schmauss M , eds Neuropsychopharmacology. Berlin, Heidelberg: Springer-Verlag, 1990.

Berrettini W Goldin L Gelernter J Gejman P Gershon E Detera-Wadleigh S . X-chromosome markers and manic depressive illness. Arch Gen Psychiatry 1990; 47:366–73.

Detera-Wadleigh S Miguel C Berrettini W DeLisi L Goldin L Gershon E . Neuropeptide gene polymorphisms in affective disorder in schizophrenia. J Psychiatr Res 1987;21:581–7.

Del Zompo M Bocchetta A Goldin L Corsini G . Linkage between X-chromosome markers in manic depressive illness. Acta Psychiatr Scand 1984;70:282–7.

Kadrmas A Winokur G . Manic depressive illness and EEG abnormalities. J Clin Psychiatry 1979;40:35–6.

Cook B Shulka S Hoff A Aronson T . Mania with associated organic factors. Acta Psychiatr Scand 1987;76:674–7.

Coryell W Endicott J Reich T Andreasen N Keller M . A family study of bipolar II disorder. Br J Psychiatry 1984;145:49–54.

Winokur G Crowe R . Bipolar illness, the sex-polarity of affectively ill family members. Arch Gen Psychiatry 1983;40:57–8.

Andreasen N Rice J Endicott J Coryell W Grove W Reich T . Familial rates of affective disorder. Arch Gen Psychiatry 1987;44:461–9.

Andreasen N Grove W Shapiro R Keller M Hirschfeld R McDonald-Scott P . Reliability of lifetime diagnosis: A multicenter collaborative perspective. Arch Gen Psychiatry 1981;38:400–5.

National Bureau of Standards Applied Mathematics, Series 6. Tables of the Binomial Probability Distribution. Washington USA: US Government Printing Office, 1949.