Does Malaria Select for Predisposition to Autoimmune Disease?

Greenwood B.M. Autoimmune disease and parasitic infections in Nigerians. Lancet 1968; i: 380–2

Lee S.L. , Siegel M. Systemic lupus erythematosus: epidemiological clues to pathogenesis. In: Dumonde D. , ed. Infection and immunology in the rheumatic diseases. Oxford: Blackwell, 1976: 307–17

Greenwood B.M. , Voller A. Suppression of autoimmune disease in New Zealand mice associated with infection with malaria. Clin Exp Immunol 1970; 7: 793–803

Greenwood B.M. , Herrick E.M. , Voller A. Suppression of autoimmune disease in NZB and (NZBxNZW) F₁ hybrid mice by infection with malaria. Nature 1970; 226: 266–7

Butcher G.A. , Clark I.A. SLE and malaria: another look at an old idea. Parasitol Today 1990; 6: 259–61

Jacob C.O. , Fronek Z.L. , Weis G.D. Proc Natl Acad Sci USA 1990; 87: 1233–7

Smolen J.S. , Chused T.M. , Leiserson W.M. Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus. Am J Med 1982; 72: 783–90

Jacob C.O. , McDevitt H.O. Tumour necrosis factor-α in murine autoimmune ‘lupus’ nephritis. Nature 1988; 331: 356–8

Satoh J.O. , Seino H. , Shigeki S. Inhibition of type 1 diabetes in BB rats with recombinant human tumor necrosis factor-α. J Immunol 1990; 145: 1395–9

Clark A. , Chaudri G. , Cowden W.B. Role of tumour necrosis factor in the illness and pathology of malaria. Trans R Soc Trop Med Hyg 1989; 83: 436–46

Kwiatowski D. , Hill A.V.S. , Sambou I. TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 1990; 336: 1201–4

Taverne J. , Bate C.A.W. , Sarkar D.A. Human and murine macrophages produce TNF in response to soluble antigens of Plasmodium falciparum. Parasite Immunol 1990; 12: 33–43

Clark I.A. Cell-mediated immunity in protection and pathology of malaria. Parasitol Today 1987; 3: 300–5

Greenwood B.M. , Coller A. , Herrick E.M. Suppression of adjuvant arthritis by infection with a strain of the rodent malaria parasite Plasmodium berghei. Ann Rheum Dis 1970; 29: 321–3

Powell R.D. , McNamara J.V. , Reickmann K.H. Clinical aspects of acquisition of immunity to falciparum malaria. Proc Helminth Soc Washington 1972; 39(special issue): 51–66

Watkinson M. , Rushton D.I. Plasmodial pigmentation of placenta and outcome of pregnancy in West African mothers. BMJ 1983; 287: 251–4

McGregor I.A. Epidemiology, malaria and pregnancy. Am J Trop Med Hyg 1984; 33: 517–25

Bruce-Chwatt L.J. A longitudenal survey of natural malaria infection in a group of West African adults. W Afr Med J 1963; 12: 141–73

Peyron F. , Vuillez J.P. , Barbe G. Plasma levels of tumor necrosis factor during a longitudenal survey in an endemic area of malaria. Acta Trop 1990; 47: 47–51

Gordon C. , Wofsy D. Effects of recombinant murine tumor necrosis factor-α on immune function. J Immunol 1990; 144: 1753–8

Butcher G.A. In vitro responses of human peripheral blood mononuclear cells to Plasmodium falciparum antigen. Int J Parasitol 1990; 20: 211–16

Butcher G.A. Mechanisms of immunity to malaria and the possibilities of a blood stage vaccine: a critical appraisal. Parasitology 1989; 98: 315–27

Goonewardene R. , Carter R. , Gamage C.P. Human T cell proliferative responses to Plasmodium vivax: evidence of immunosuppression following prolonged exposure to endemic malaria. Eur J Immunol 1990; 20: 1201–16

Taverne J. , Bate C.A.W. , Playfair J.H.L. Malaria exo-antigens induce TNF, are toxic and are blocked by T-independent antibody. Immunol Lett 1990; 25: 207–12

Brown A.E. , Webster H.K. , Teja-Isavadharm P. Macrophage activation in falciparum malaria as measured by neopterin and interferon gamma. Clin Exp Immunol 1990; 82: 97–101

Velde te A.A. , Huijbens J.F. , Heije K. Interleukin-4 inhibits secretion of IL-1β, tumor necrosis factor, and IL-6 by human monocytes. Blood 1990; 76: 1392–7

Schindler R. , Mancilla J. , Endres S. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood 1990; 75: 40–7

Troye-Blomberg M. , Riley E.M. , Kabilan L. Production by activated human T cells of interleukin 4 but not interferon -γ is associated with elevated levels of serum antibodies to activating malaria antigens. Proc Natl Acad Sci USA 1990; 87: 5484–8

Corelli F. Malarial therapy in Buerger's disease. Med World 1959; 91: 529–39

Yamada Y. , Kimball K. , Okusawa S. Cytokines, acute phase proteins, and tissue injury. Ann NY Acad Sci 1990; 587: 351–61

Sinha A.A. , Lopez M.T. , McDevitt H.O. Autoimmune diseases: the failure of self-tolerance. Science 1990; 248: 1380–7