Recent Advances in Systemic Vasculitis

Cavender D.E. , Haskard D.O. , Joseph B. , Ziff M. Inter-leukin-1 increases the binding of human B and T lymphocytes to endothelial cell monolayers. J Immunol 1986; 136: 203–7

Cavender D.E. , Saegusa Y. , Ziff M. Stimulation of endothelial cell binding of lymphocytes by tumour necrosis factor. J Immunol 1987; 139: 1855–60

Thornhill M. , Kyan-Aung U. , Lee T.L. , Haskard D.O. T cells and neutrophils exhibit differential adhesion to cytokine stimulated endothelial cells. Immunology 1990 (in press)

Yu C.L. , Haskard D.O. , Cavender D.E. , Johnson A.R. , Ziff M. Human gamma interferon increases the binding of T lymphocytes to endothelial cells. Clin Exp Immunol 1985; 62: 554–61

Stern D.M. , Bank I. , Nawroth P.P. Self-regulation of procoagulant events on the endothelial cell surface. J Exp Med 1985; 162: 1223–35

Libby P. , Ordovas J.M. , Birinyi L.K. , Auger K.R. , Dinarello C.A. Inducible interleukin-1 gene expression in human vascular smooth muscle cells. J Clin Invest 1986; 78: 1432

Warner S.J.C. , Libby P. Human vascular smooth muscle cells: target for and source of tumour necrosis factor. J Immunol 1989; 142: 100–9

Cavender D.E. , Haskard D.O. , Maliakkal D. , Ziff M. Separation and characterization of human T lymphocytes with varying adhesiveness for endothelial cells in vitro: evidence for preferential binding of natural killer cells. J Clin Invest 1988; 79: 1679–88

Bender J.R. , Pardi R. , Karasek M.A. , Engleman E.G. Phenotypic and functional characterization of lymphocytes that bind human microvascular endothelial cells in vitro: evidence for preferential binding of natural killer cells. J Clin Invest 1987; 79: 1679–88

Pitzalis C. , Kingsley G. , Haskard D.O. , Panayi G.S. The preferential accumulation of helper-inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion. Eur J Immunol 1988; 18: 1397–1404

Nagai K. , Katori M. Possible changes in the leukocyte membrane as a mechanism of leukocyte adhesion to the venular walls induced by leukotriene B₄ and fMLP in the microvasculature of the hamster cheek pouch. Int J Microcir 1988; 7: 305–14

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Hoover R.L. , Karnovsky M.J. , Austen K.F. , Corey E.J. , Lewis R.A. Leukotriene B₄ action on endothelium mediates augmented neutrophil/endothelial adhesion. Proc Natl Acad Sci USA 1984; 81: 2191–3

Tonnesen M.G. , Smedley L.A. , Henson P.M. Neutrophilendothelial cell interactions. Modulation of neutrophil adhesiveness induced by complement fragments C5a and C5a des arg and formyl-methionyl-leucyl-phenylalanine in vitro. J Clin Invest 1984; 74: 1581–2

Colditz I.G. , Movat H.Z. Desensitization of acute inflammatory lesions to chemotaxins and endotoxin. J Immunol 1984; 133: 2163–8

Cybulsky M.I. , Chan M.K.W. , Movat H.Z. Biology of disease: acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection. Lab Invest 1988; 58: 365–78

Rampart M. , Williams T.J. Evidence that neutrophil accumulation induced by interleukin-1 requires both local protein biosynthesis and neutrophil CD18 antigen expression in vivo. Br J Pharmacol 1988; 94: 1143–8

Bevilazqua M.R. , Pober J.S. , Wheeler M.E. , Cotran R.S. , Gimbrone M.A. Interleukin-1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leucocytes, monocytes and related cell lines. J Clin Invest 1985; 76: 2003–11

Beatty P.G. , Ledbetter J.A. , Martin P.J. , Price T.H. , Hansen J.A. Definition of a common leukocyte cell-surface antigen (Lp95-150) associated with diverse cell-mediated immune functions. J Immunol 1983; 131: 2913–18

Springer T.A. , Thompson W.S. , Miller L.G. , Schmalstieg F.C. , Anderson D.C. Inherited deficiency of the Macl, LFA-1, p150/95 glycoprotein family and its molecular basis. J Exp Med 1984; 160: 1901–18

Wallis W.J. , Hickstein D.D. , Schwartz B.R. Monoclonal antibody-defined functional epitopes on the adhesion-promoting glycoprotein complex (CDw18) of human neutrophils. Blood 1986; 67: 1007–13

Arfors K.E. , Lundberg C. , Lindbom L. , Lundberg K. , Beatty P.G. , Harlan J.M. A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo. Blood 1987; 69: 338–40

Nourshargh S. , Rampart M. , Hellewell P.G. Accumulation of ¹¹¹In-neutrophils in rabbit skin in allergic and non-allergic inflammatory reactions in vivo: inhibition by neutrophil pretreatment in vitro with a monoclonal antibody recognising the CD18 antigen. J Immunol 1989; 142: 3193–8

Vedder N.B. , Harlan J.M. Increased surface expression of CDllb/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium. J Clin Invest 1988; 81: 676–82

Philips M.R. , Buyon J.P. , Winchester R. , Weissmann G. , Abramson S.B. Up regulation of the iC3b receptor (CR3) is neither necessary nor sufficient to promote neutrophil aggregation. J Clin Invest 1988; 82: 495–501

Wedmore C.V. , Williams T.J. Control of vascular permeability by polymorphonuclear leukocytes in inflammation. Nature 1981; 289: 646–50

Jose P.J. , Forrest M.J. , Williams T.J. Human C5a des Arg increases vascular permeability. J Immunol 1981; 127: 2376–80

Williams T.J. Prostaglandin E₂, prostaglandin I₂ and the vascular changes of inflammation. Br J Pharmacol 1979; 65: 517–24

Williams T.J. Vasoactive intestinal polypeptide is more potent than prostaglandin E₂ as a vasodilator and oedema potentiator in rabbit skin. Br J Pharmacol 1982; 77: 505–9

Brain S.D. , Williams T.J. Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability. Br J Pharmacol 1985; 86: 855–60

Godman G.C. , Churg J. Wegener's Granulomatosis: pathology and review of the literature. Arch Pathol 1954; 58: 533–53

Fauci A.S. , Haynes B.F. , Katz P. , Wolff S.M. Wegener's Granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med 1983; 98: 76–85

Van der Woude F.J. , Rasmussen N. , Lobatto S. The TH. Auto-antibodies to neutrophils and monocytes: A new tool for diagnosis and marker of disease activity in Wegener's Granulomatosis. Lancet 1985; i: 425–9

Gross W.L. , Luedemann G. , Kiefer G. , Lehmann H. Anticytoplasmic antibodies in Wegener's Granulomatosis (letter). Lancet 1986; i: 806

Savage C.O. , Winearls C.G. , Jens S. , Marshall P.D. , Lockwood C.M. Prospective study of radioimmunoassay for antibodies against neutrophil cytoplasm in diagnosis of systemic vasculitis. Lancet 1987; i: 1389–93

Venning M.C. , Arfeen S. , Bird A.G. Antibodies to neutrophil cytoplasmic antigen in systemic vasculitis (letter). Lancet 1987; i: 1037

Noelle B. , Specks U. , Luedemann J. , Rohrbach M.S. , De Remee R.A. , Gross W.L. Anticytoplasmic autoantibodies: their immunodiagnostic value in Wegener's Granulomatosis. Ann Intern Med 1989; 111: 28–40

Falk R.J. , Jennette J. Anti-neutrophil cytoplasmic antibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 1988; 318: 1651–7

Van der Woude F.J. , Daha M.R. , Van Es L.A. The current status of neutrophil cytoplasmic antibodies. Clin Exp Immunol 1990

Van den Wall bake A.W.L. , Lobatto S. , Jonges L. , Daha M.R. , Van Es L.A. IgA antibodies directed against cytoplasmic antigens of polymorphonuclear leucocytes in patients with Henoch-Schoenlein purpura. In: Mestecky J. Recent advances in mucosal immunology, Part B. New York: Plenum1987: 1593–8

Penning C.A. , Jones S. , Lockwood C.M. Antibody binding profiles of sera from systemic vasculitis patients (Abstr). Abstract book XXVth Congress of the European Dialysis and Transplant Association Madrid, Spain 1988: 53

Wiik A. Deliniation of a standard procedure for indirect immunofluorescence detection of ANCA. APMIS 1989; 97(Suppl 6): 12

Rasmussen N. , Borregaard N. , Wieslander J. , Worsaa A. Alpha-ELISA determination of ANCA and characterization of the ANCA-related antigen. APMIS 1989; 97(Suppl 6): 40

Baugh R.J. , Travis J. Human leucocyte granule elastase: rapid isolation and characterization. Biochemistry 1976; 97: 52

Goldschmeding R. , Ten Bokkel Huinink D. , Faber N. Identification of the ANCA antigen as a novel myeloid lysosomal serine proteinase. APMIS 1989; 97(Suppl 6): 46

Luedemann J. , Utecht B. , Gross W.L. Partial characterization of the ACPA-autoantigen. In: van der Woude F.J. ed. Proceedings of the 2nd International ANCA workshop. Neth J Med 1990 (in press)

Daha M.R. , Kramps J.A. , Schrama E. , Van Es L.A. , Van der Woude F.J. Isolation from purulent sputum of an antigen reactive with antibodies in Wegener's serum. In: van der Woude F.J. , ed. Proceedings of the 2nd International ANCA workshop. Neth J Med 1990 (in press)

Goldschmeding R. , Van der Schoot C.E. , Van der Snoek M.E. , Von dem Borne AEGK . A monoclonal antibody against the 29 kD ANCA antigen: Application as catching antibody against the 29 kD ANCA-antigen. APMIS 1989; 97(Suppl 6): 4

Daha M.R. , Rasmussen N. Presentation of solid phase assays from several laboratories. In: van der Woude F.J. , ed. Proceedings of the 2nd International ANCA workshop. Neth J Med 1990 (in press)

Wegener F. Uber eine eigenartige rhinogene Granulomatose mit besonderen Beteligung des Arterien system und der Nieren. Betr Pathol Anat 1939; 102: 37

Pinching A.J. , Rees A.J. , Pussel B.A. , Lockwood C.M. , Mitchison R.S. , Peters D.K. Relapses in Wegener's Granulomatosis: the role of infection. Br Med J 1980; 281: 836–8

De Remee R.A. , McDonald T.J. , Weiland L.H. Wegener's Granulomatosis: Observation on treatment with antimicrobial agents. Mayo Clin Proc 1985; 60: 27

Van der Woude F.J. , Van Es L.A. , Daha M.R. The role of the cANCA-antigen in the pathogenesis of Wegener's Granulomatosis. A hypothesis based on both humoral and cellular mechanisms. In: van der Woude F.J. , ed. Proceedings of the 2nd International ANCA workshop. Neth J Med 1990 (in press)

Jennette J.C. , Wilman A.S. , Falk R.J. Anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and vasculitis. Am J Pathol 1989; 135: 921–30

Falk R.J. , Jennette J.C. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Eng J Med 1988; 318: 1651–7

Goldschmeding R. , van den Schoot C.E. , Ten Bokkel Huinink D. Wegener's granulomatosis autoantibodies identify a novel dilsopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils. J Clin Invest 1989; 84: 1577–87

Charles L.A. , Falk R.J. , Jennette J.C. Reactivity of antineutrophil cytoplasmic autoantibodies with HL-60 cells. Clin Immunol Immunopathol 1989; 53: 243–53

Niles J.L. , McCluskey R.T. , Ahmad M.F. , Arnaout M.A. Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase. Blood 1989; 74: 1888–93

Lesavre P. , Chen N. , Nusbaum P. , Mecarelli L. , Noel L.H. Antineutrophil cytoplasm antibodies (ANCA) with antilactoferrin activity in vasculitis. Kidney Int 1990; 37: 443

Falk R.J. , Hogan S.L. , Jennette J.C. NC Glomerular Disease Collaborative Network: A prospective cohort study of 70 patients with anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis. Kidney Int 1990; 37: 256

Falk R.J. , Terrell R.S. , Charles L.A. , Jennette J.C. Leukocyte activation by anti-neutrophil cytoplasmic autoantibodies: a potential mechanism of immune vascular injury. Clin Res 1989; 37: 490a

Jennette J.C. , Terrell R.S. , Charles L.A. , Falk R.J. Evidence for the pathogenetic potential of anti-neutrophil cytoplasmic autoantibodies. Kidney Int 1990; 37: 441

Nolle B. , Specks U. , Ludemann J. , Rohrbach M.S. , DeRemee R.A. , Gross W.L. Anticytoplasmic Autoantibodies: Their Immunodiagnostic Value in Wegener Granulomatosis. Ann Intern Med 1989; 111: 28–40

Kao R.C. , Wehner N.G. , Skubitz K.M. , Gray B.H. , Hoidal J.R. Proteinase 3: a distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters. J Clin Invest 1988; 82: 1963–73

Ludemann J. , Utecht B. , Gross W.L. Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme. J Exp Med 1990 (in press)

Csernok E. , Ludemann J. , Gross W.L. , Bainton D.F. Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis. Submitted.

Deremee R.A. The treatment of Wegener's granulomatosis with Trimethoprim/Sulfamethoxazole: illusion or vision? Arthritis Rheum 1989; 31: 1068–73

Pusey C.D. , Lockwood C.M. Plasma exchange for glomerular disease. In: Robinson R.R. , ed. Nephrology, New York: Springer-Verlag, 1984

Jayne D.R.W. , Rossi F. , Kazatchkine M.D. , Lockwood C.M. Anti-idiotypes against autoantibodies to neutrophil cytoplasmic antigens are present in pooled human immunoglobulin and post-recovery sera. 7th International Congress of Immunology, 1989: 273 (abstract)