Seventy-three group B adenoviruses (29 type 3 and 44 type 7) identified in a recent community outbreak were analysed with restriction endonucleases. Considerable genetic heterogeneity was identified, particularly amongst the type 3 isolates, but this genome variation could not be correlated with either clinical or epidemiological findings. Group F adenoviruses were found in 132 (4.1%) of 3202 stool specimens from children with gastroenteritis and, after rotaviruses, they were the most common viruses identified. Unlike rotaviruses, these enteric adenoviruses were endemic throughout the 3–year study period and the greatest proportion of infections (47.6%) were found in babies under 6 months old.
BrownR.S., NogradyM.B., SpenceL., WigglesworthF.W.An outbreak of adenovirus type 7 infection in children in Montreal. Can Med Assoc J1973; 108: 434–9
2.
UhnooI., WadellG., SvenssonL., JohanssonM.E.Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children. J Clin Microbiol1984; 20: 365–72
3.
WadellG.Molecular epidemiology of human adenoviruses. Curr Top Microbiol Immunol1984; 110: 191–230
4.
BaileyA.S., RichmondS.J.Genetic heterogeneity of recent isolates of adenovirus types 3, 4 and 7. J Clin Microbiol1986; 24: 30–5
5.
WoodD.J., BaileyA.S.Immune electron microscopy for adenovirus types 40 and 41 in stool specimens. J Med Virol1987; 21: 191–9
6.
GrahamF.L., SmileyJ., RussellW.C., NairnR.Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol1977; 36: 59–72
7.
WadellG., HammarskjoldM.L., WinbergG., VarsanyiT.M., SundellG.Genetic variability of adenoviruses. Ann N Y Acad Sci1980; 354: 16–42
8.
KiddA.H.Genome variants of adenovirus 41 (subgroup G) from children with diarrhoea in Africa. J Med Virol1984; 14: 49–59
9.
O'DonnellB., BellE., PayneS.B., MautnerV., DesselbergerU.Genome analysis of species 3 adenoviruses isolated during summer outbreaks of conjunctivitis and pharyngo-conjunctival fever in the Glasgow and London areas in 1981. J Med Virol1986; 18: 213–27
10.
MadelyC.R.The emerging role of adenoviruses as inducers of gastroenteritis. Pediatr Infect Dis1986; 5: 563–74
ChampsaurH., QuestiauxE., PrevotJ.Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. I. Virus shedding. J Infect Dis1984; 149: 667–74
