The most common sites for Paget's disease of the spine are the sacrum followed by the lumbar spine1, but paraparesis is more common with dorsal involvement. Over 100 cases of dysfunction of the spinal cord or cauda equina secondary to Paget's disease of the vertebral column have been described since it was first reported by Wyllie2. We report a patient with paraparesis secondary to Paget's disease of the dorsal vertebrae with complete myelographic obstruction, who was treated medically with disodium etidronate.
DouglasD.L., DuckworthT., KanisJ.A., JeffersonA.A., MartinT.J., RussellR.C.G.. Spinal cord dysfunction in Paget's disease of bone. Has medical treatment a vascular basis?J Bone Joint Surg1981; 63B: 495–503
5.
SadarE.S., WaltonR.J., GossmanH.M.. Neurological dysfunction in Paget's disease of the vertebral column.J Neurosurg1972; 37: 661–5
6.
SchmidekH.H.. Neurologic and neurosurgical sequelae of Paget's disease of bone.Clin Orthop1977; 127: 70–7
7.
HartmanJ.T., DohnD.F.. Paget's disease of the spine with cord or nerve root compression.J Bone Joint Surg1966; 48A: 1079–84
8.
KlenermanL.. Cauda equina and spinal cord compression in Paget's disease.J Bone Joint Surg1966; 48B: 365–70
9.
SingerF.R.. Paget's disease of bone.New York: Plenum Press, 1977
10.
HadjipavlouA.G., TsoukasG.M., SillerT.N., DanaisS., GreenwoodF.. Combination drug therapy in treatment of Paget's disease of bone.J. Bone Joint Surg1977; 59A: 1045–51
11.
ShaiF., BakerR.K., WallachS.. The clinical and metabolic effects of porcine calcitonin on Paget's disease of bone.J Clin Invest1971; 50: 1927–40
12.
MelickR.A., EbelingP., HjorthR.J.. Improvement in paraplegia in vertebral Paget's disease treated with calcitonin.Br Med J1976; i: 627–8
13.
NicolleM-H, GrondardE., FrancoisN., MauryM.. A propos d'une paraplégie Pagétique traitée avec succés par la calcitonine avec un recul de plus de 4 ans.Therapie1977; 32: 603–9
14.
SchumacherM., LevyA., BeckU., RemagenW.. Paget's disease with spinal cord compression: favourable course after decompression and calcitonin treatment in two cases.Eur Neurol1977; 15: 116–20
15.
AlexandreC., TrilletM., MeunierP., FischerC.. Traitement des paraplégies Pagétiques par les diphosphonates.Rev Neurol (Paris)1979; 135: 625–32
16.
ChenJ-R, RheeR.S.C., WallachS., AvramidesA., FloresA.. Neurologic disturbances in Paget's disease of bone: response to calcitonin.Neurology1979; 29: 448–57
17.
RavichandronG.. Neurologic recovery of paraplegia following use of salmon calcitonin in a patient with Paget's disease of spine.Spine1979; 4: 37–40
18.
WalpinL.A., SingerF.R.. Paget's disease; reversal of severe paraparesis using calcitonin.Spine1979; 4: 213–9
19.
HerzbergL., BaylissE.. Spinal cord syndrome due to non-compressive Paget's disease of bone: a spinal artery steal phenomenon reversible with calcitonin.Lancet1980; ii: 13–5
