Growth hormone releasing factors

Dueben R.R. , Meites J. Stimulation of pituitary growth hormone release by a hypothalamic extract in vitro. Endocrinology 1964; 74: 408–14

Ling N. , Esch F. , Bohlen P. , Brazeau P. , Wehrenberg W.B. , Guillemin R. Isolation, primary structure, and synthesis of human hypothalamic somatocrinin; Growth hormone-releasing factor. Proc Natl Acad Sci USA 1984; 81: 4302–6

Guillemin R. , Brazeau P. , Bohlen P. , Esch F. , Ling N. , Wehrenberg W.B. Growth hormone-releasing factor from a human pancreatic tumour that caused acromegaly. Science 1982; 218: 585–7

Rivier J. , Spiess J. , Thorner M. , Vale W. Characterisation of a growth hormone-releasing factor from a human pancreatic islet tumour. Nature 1982; 300: 276–8

Ling N. , Baird A. , Wehrenberg W.B. , Ueno N. , Munegumi T. , Brazeau P. Synthesis and in vitro bioactivity of C-terminal deleted analogs of human growth hormone-releasing factor. Biochem Biophys Res Commn 1984; 123: 854–61

Ling N. , Baird A. , Wehrenberg W.B. Synthesis and in vitro bioactivity of human growth hormonereleasing factor analogs substituted at position −1. Biochem Biophys Res Commun 1984; 122: 301–10

Bloch B. , Brazeau P. , Ling N. Immunohistochemical detection of growth hormone-releasing factor in brain. Nature 1983; 301: 607–8

Christofides N.D. , Stephanou A. , Suzuki H. , Yiangou Y. , Bloom S.R. Distribution of immunoreactive growth hormone-releasing hormone in the human brain and intestine and its production by tumours. J Clin Endocrinol Metab 1984; 59: 747–51

Shibasaki T. , Kiyosawa Y. , Masuda A. Distribution of growth hormone-releasing-hormone-like immuno-reactivity in human tissue extracts. J Clin Endocrinol Metab 1984; 59: 263–8

Sopwith A.M. , Penny E.S. , Besser G.M. , Rees L.H. Stimulation by food of peripheral plasma immunoreactive growth hormone releasing factor. Clin Endocrinol 1985; 22: 337–40

Thorner M.O. , Frohman L.A. , Leong D.A. Extra-hypothalamic growth hormone releasing factor (GRF) secretion is a rare cause of acromegaly; plasma GRF levels in 177 acromegalic patients. J Clin Endocrinol Metab 1984; 59: 846–9

Sandler L.M. , Burrin J.M. , Joplin G.F. , Bloom S.R. Combined use of vasopressin and synthetic hypothalamic releasing factors as a new test of anterior pituitary function. Br Med J 1986; 292: 511–14

Looij B.J. , Kruseman A.C.N. , Mudde A.H. The interaction of growth hormone releasing hormone with other hypothalamic hormones on the release of anterior pituitary hormones. Clin Endocrinol 1986; 24: 149–56

Schriock E.A. , Lustig R.H. , Rosenthal S.M. , Kaplan S.L. , Grumbach M.M. Effect of growth hormone (GH)-releasing hormone (GRH) on plasma GH in relation to magnitude and duration of GH deficiency in 26 children and adults with isolated GH deficiency or multiple pituitary hormone deficiencies; evidence for hypothalamic GRH deficiency. J Clin Endocrinol Metab 1984; 58: 1043–9

Takano K. , Hizuka N. , Shizume K. , Ling N.C. Plasma GH response to hpGRF 1–44 in normal children of short stature and patients with GH deficiency. Endocrinol Japan 1984; 31: 41–8

Davies R.R. , Parkin J.M. , Turner S.J. , Cook D.B. , Johnston D.G. The growth hormone response to growth hormone releasing factor 1–44 and somatomedin-C levels in the diagnosis of growth failure. J Endocrinol Invest 1985; 8(Suppl 3): 79

Powell-Jackson J. , Weller R.O. , Kennedy P. , Preece M.A. , Whitcombe E.M. , Newsom-Davis J. Creutzfeldt-Jacob disease after administration of growth hormone. Lancet 1985; ii: 244–6

Koch T.K. , Berg B.O. , De Armond S.J. , Cravina R.F. Creutzfeldt-Jacob disease in a young adult with idiopathic hypopituitarism. N Engl J Med 1985; 313: 731–3

Gibbs C.J. , Joy A. , Heffner R. Clinical and pathological features and laboratory confirmation of Creutzfeldt-Jacob disease in a recipient of pituitary derived human growth hormone. N Engl J Med 1985; 313: 734–8

Taylor D.M. , Dickinson A.G. , Fraser H. , Robertson P.A. , Salacinski P.R. , Lowry P.J. The preparation of growth hormone free from contamination with unconventional slow viruses. Lancet 1985; ii: 260–2

Smith P.J. , Brook C.G.D. , Pringle P.J. , Rivier J. , Vale W. , Thorner M.O. The induction of growth hormone secretion following long term treatment of growth hormone deficient children with growth hormone releasing hormone 1–40. J Endocrinol Invest 1985; 8(Suppl 3): 81

Ross R.J.M. , Grossman A. , Davies P. Evaluation of long-term subcutaneous GRF (1–29) NH₂ as treatment of growth hormone deficiency. J Endocrinol Invest 1985; 8(Suppl 3): 80

Kaplan S.L. , Underwood L.E. , August G.P. Clinical studies with recombinant-DNA-derived methionyl human growth hormone in growth hormone deficient children. Lancet 1986; i: 697–700