Glycosylated haemoglobin (HbAl), as an assessment of overall control, was estimated in 858 insulin-treated diabetics attending for changeover to U100 insulin in North East Wales. Details of age, sex, duration of diabetes, insulin regimen and monitoring method were recorded. Multivariate analysis revealed lower HbAl in patients receiving twice-daily (mean 11.01) as compared with once-daily insulin (11.42, P=0.011), but no difference was found between urine and blood glucose testers when other variables were taken into consideration. HbAl was lower in men (mean 10.94) compared with women (mean 11.39, P=0.004) and there was a positive correlation of HbAl in men with age (P= 0.046) and in women with duration of disease (P=0.005).
References
1.
BlockM BRosenfieldR LMakoM ESteinerD FRubensteinA H (1973) New England Journal of Medicine288, 1144–1148.
2.
DunnP JColeR ASoeldnerJ SGleasonR E (1979) Annals of Internal Medicine91, 390–396.
3.
GoldsteinD EWalkerBRawlingsS S (1980) Diabetes Care3, 503–507.
4.
GonenBRochmanHRubensteinA H (1979) Metabolism28, 448–452.
5.
GonenBRubensteinA HRochmanHTanegaS PHorwitzD L (1977) Lancetii, 734–736.
6.
KoenigR JPetersonC MJonesR LSaudekCLehrmanMCeramiA (1976) New England Journal of Medicine295, 417–420.
7.
NieN HHullC HJenkinsJ G (1975) SPSS. Statistical Package for the Social Sciences. 2nd edn.McGraw Hill, New York.
8.
PaiseyR BBradshawPBurkeB JMacFarlaneDCHartogM (1982) Journal of the Royal College of Physicians of London16, 108–112
9.
SonksenP HJuddS LLowyC (1978) Lanceti, 729–732.
10.
SticklandM HPatonR CWalesJ K (1984) British Medical Journal289, 733.
11.
WalfordSAllisonS PReevesW G (1982) Diabetologia22, 106–110.
12.
WalfordSGaleE A MAllisonS PTattersallR B (1978) Lanceti, 732–735.
13.
WalshC HMalinsJ M (1977) British Medical Journalii, 177–179.
14.
WatkinsP J (1982) British Medical Journal284, 1929–1932.
15.
WertherG ATurnerR CJenkinsP ABaumJ D (1982) Diabetologia22, 245–249.
16.
WorthR CHomeP DJohnstonD G (1982) British Medical Journal285, 1235–1240.
