The effects of partial ileal bypass have been studied in 7 patients with heterozygous familial hypercholesterolaemia. By the seventh to ninth postoperative day there was a significant fall in plasma cholesterol of 42.8% compared with levels at initial presentation. Thereafter, plasma levels of cholesterol rose by varying degrees, but had stabilized by 3 months with average values 29.5% lower than pretreatment. Debilitating diarrhoea or severe weight loss were not troublesome features of the operation in most patients.
References
1.
BrayG A (1976) The Obese Patient. W B Saunders, Philadelphia; pp 411–445
2.
BuchwaldHMooreR BVarcoR L (1974) Circulation49, Suppl. 1; pp 1–3
3.
BuchwaldHMooreR BVarcoR L (1981) In: Atherosclerosis V. Ed. GottoA MSpringer, Berlin; pp 462–465
4.
IllingworthD RPhillipsonB ERappF HConnorW E (1981) Lanceti, 296–298
5.
MiettinenT ALempinenM (1977) European Journal of Clinical Investigation7, 509–514
6.
RussellDFritzVMienyC JMendelsohnDJoffeB ISeftelH C (1979) South African Medical Journal55, 237–240
7.
SoutarA KMyantN BThompsonG R (1977) Atherosclerosis28, 247–256
8.
SpengelF AJadhavADuffieldR G MWoodC BThompsonG R (1981) Lancetii, 768–770
