JonesP.T., DearP.H., FooteJ.. Replacing the complementarity-determining regions in a human antibody with those from a mouse.Nature1986; 321: 522–5
6.
ReffM.E., HariharanK., BraslawskyG.Future of monoclonal antibodies in the treatment of hematologic malignancies.Cancer Control2002; 9: 152–66
7.
McLaughlinP., Grillo-LopezJ., WhiteC.. IDEC-C2B8 rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.J Clin Oncol1998; 16: 2825–33
8.
DavisT., Grillo-LopezJ., WhiteC.. Rituximab anti-CD20 monoclonal antibody therapy in non-Hodgkin's lymphoma: safety and efficacy of retreatment.J Clin Oncol2000; 18: 3135–43
9.
MarcusR., ImrieK., BelchA.. An international multi-centre, randomised open-label phase III trial comparing rituximab added to CVP chemotherapy to CVP chemotherapy alone in untreated stage III/IV follicular non-Hodgkin's lymphoma.Blood2003; 102: Abstr 87
10.
CoiffierB., LepageE., BriereJ.. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma.N Engl J Med2002; 346: 235–42
11.
CoiffierB., HerbrechtR., TillyH.. GELA study comparing CHOP and R-CHOP in elderly patients with DLCL: 3-year median follow-up with analysis according to co-morbidity factors.Proc Am Soc Clin Oncol2003; 22: 596
12.
MounierN., BriereJ., GisselbrechtC.. Rituximab and CHOP (R-CHOP) overcomes bcl2-associated resistance to chemotherapy in elderly patients with diffuse large B cell lymphoma (DLBCL).Blood2003; 101: 4279–84
13.
DemidemA., LamT., AlasS.. Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs.Cancer Biother Radiopharm1997; 12: 177–86
14.
JohnsonT.A., PressO.W.Synergistic cytotoxicity of iodine-131-anti-CD20 antibodies and chemotherapy for treatment of B-cell lymphomas.Int J Cancer2000; 85: 104–12
15.
RayzmanV., ScottA.Monoclonal antibodies for cancer therapy.Cancer Forum2002; 26: 104–8
16.
ByrdJ., MurphyT., HowardR.. Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small cell lymphocytic lymphoma demonstrated clinical activity and acceptable toxicity.J Clin Oncol2001; 19: 2153–64
HainsworthJ., LitchyS., BartonJ.. Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small-cell lymphocytic lymphoma: a phase II trial of the Minnie Pearl Cancer Research Network.J Clin Oncol2003; 21: 1746–51
19.
ByrdJ., PetersenB., ParkK.. Concurrent rituximab and fludarabine has a higher complete response rate than sequential treatment in untreated chronic lymphocytic leukemia patients: results from CALGB 9712.Blood2001; 98: Abstr 772
20.
WitzigT., WhiteC., WisemanG.. Phase I/II trial of IDEC-Y2B8 radioimmunotherapy for treatment of relapsed or refractory CD20(+) B-cell non-Hodgkin's lymphoma.J Clin Oncol1999; 17: 3793–803
21.
WitzigT., FlinnI., GordonL.. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab refractory follicular NHL.J Clin Oncol2002; 20: 3262–9
22.
WitzigT., GordonL., CabanillasF.. Randomised control trial of Yttrium 90-labelled ibritumomab tiuxetan radioimmunotherapy versus rituximab immunotherapy for patients with relapsed or refractory low-grade follicular or transformed B-cell non-Hodgkin's lymphoma.J Clin Oncol2002; 20: 2453–63
23.
KaminskiM., ZelenetzA., PressO.. Pivotal study of iodine 131 tositumomab for chemotherapy-refractory low-grade or transformed low-grade non-Hodgkin's lymphomas.J Clin Oncol2001; 19: 3918–28
24.
KaminskiM., EstesJ., ReganD.. Front-line treatment of advanced B-cell low-grade lymphoma with radiolabelled anti-B1 antibody: initial experience.Proc Am Soc Clin Oncol1997; 16: 15a
25.
DillmanR.Radiolabelled anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoma.J Clin Oncol2002; 20: 3545–57
PorebskaI., HarlozinskaA., BojarowskiT.Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERBB2, ERBB3) in colorectal adenocarcinomas and adenomas.Tumor Biol2000; 21: 105–15
28.
SalomonD.S., BrandtR., CiardielloF., NormannoN.Epidermal growth factor-related peptides and their receptors in human malignancies.Crit Rev Oncol Haematol1995; 19: 183–232
29.
SaltzL., RubinM.S., HochsterH.S.. Cetuximab (IMC-C225) plus irinotecan (CPT-11) is active in CPT-11 refractory colorectal cancer that expresses epidermal growth factor receptor.Proc Am Soc Clin Oncol2001; 20: Abstr 3
30.
SaltzL.B., MeropolN.J., LoehrerPJSr. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.J Clin Oncol2004; 22: 1201–8
31.
CunninghamD., HumbletY., SienasS.. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan refractory metastatic colorectal cancer.N Engl J Med2004; 351: 337–45
32.
RobertF., EsekielM., SpencerS.. Phase I study of anti-epidermal growth-factor receptor cetuximab in combination with radiation therapy in patients with advanced head and neck cancer.J Clin Oncol2001; 19: 3234–43
33.
AbbruzzeseJ., RosenbergA., XiongQ.. Phase II study of anti-epidermal growth factor receptor (EGFR) antibody cetuximab (IMC-C225) in combination with gemcitabine in patients with advanced pancreatic cancer.Proc Am Soc Clin Oncol2001; 20: 130a
34.
GatzemeierU., RosellR., RamlauR.. Cetuximab in combination with cisplatin/vinorelbine vs cisplatin/vinorelbine alone in the firstline treatment of patients with epidermal growth-factor receptor expressing advanced non-small-cell lung cancer.Proc Am Soc Clin Oncol2003; 22: Abstr 642
35.
SaltzL., KiesM., AbbruzzeseJ.. The presence and intensity of the cetuximab-induced acne-like rash predicts increased survival in studies across multiple malignancies.Proc Am Soc Clin Oncol2003; 22: 204
36.
BergerM.S., LocherG.W., SaurerS.. Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.Cancer Res1988; 48: 1238–43
37.
SlamonD.J., GodolphinW., JonesL.A.. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer.Science1989; 244: 707–12
38.
BorgA., BaldetorpB., FernöM.ERBB2 amplification in breast cancer with a high rate of proliferation.Oncogene1991; 6: 137–43
39.
StålO., CarstensenJ.M., WingrenS.Relationship of DNA ploidy and S-phase fraction to survival after first recurrence of breast cancer.Acta Oncol1994; 33: 423–9
40.
QuénelN., WafflartJ., BonichonF.The prognostic value of c-erbB2 in primary breast carcinomas: a study on 942 cases.Breast Cancer Res Treat1995; 35: 283–91
41.
SlamonD.J., ClarkG.M., WongS.G.. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene.Science1987; 385: 177–81
42.
SlamonD.J., Leyland-JonesB., ShakS.. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.N Engl J Med2001; 344: 783–92
43.
OsabaD., SlamonD., BurchmoreM.. Effects on quality of life of combined trastuzumab and chemotherapy in women with metastatic breast cancer.J Clin Oncol2002; 20: 3106–13
44.
SeidmanA., HudisC., PierriM.. Cardiac dysfunction in the trastuzumab clinical-trial experience.J Clin Oncol2002; 20: 1215–21
45.
SchneiderJ.W., ChangA.Y., RoccoT.P.Cardiotoxicity in signal transduction therapeutics: erbB2 antibodies and the heart.Semin Oncol2001; 28(suppl): 18–26
46.
PegramM.D., SlamonD.J.Combination therapy with trastuzumab (Herceptin) and cisplatin for chemoresistant metastatic breast cancer: evidence for receptor-enhanced chemosensitivity.Semin Oncol1999; 26: 89–95
47.
RosenL.S.Clinical experience with angiogenesis signaling inhibitors: focus on vascular endothelial growth factor (VEGF) blockers.Cancer Control2002; 9(suppl): 36–44
48.
HurwitzH., FehrenbacherL., CartwrightT.. Bevacizumab a monoclonal antibody to vascular-endothelial growth factor prolongs survival in first-line colorectal cancer: results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5 fluorouracil, leucovorin) as first-line therapy in subjects with metastatic colorectal cancer.Proc Am Soc Clin Oncol2003; 22: Abstr 3646
49.
YangJ.C., HaworthL., SherryR.M.. A randomised trial of bevacizumab, an anti-vascular-endothelial growth-factor antibody for metastatic renal cancer.N Engl J Med2003; 349: 427–34
50.
JohnsonD.H., FehrenbacherL., NovotnyW.F.. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer.J Clin Oncol2004; 22: 2184–91
51.
MillerK., RugoH., CobleighM.. Phase III trial of capecitabine plus bevacizumab versus capecitabine alone in women with metastatic breast cancer previously treated with anthracycline and a taxane.Breast Cancer Res Treat2002; 76(suppl): Abstr 36
52.
GriffinJ., LinchD., SabbathK.. A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells.Leuk Res1984; 8: 521–34
53.
SchedinbergD., LovettD., DivgiC.. A phase I trial of monoclonal antibody M195 in acute myelogenous leukemia: specific bone-marrow targeting and internalisation of radionuclide.J Clin Oncol1991; 9: 478–90
54.
SieversE., LarsonR., StadtmauerE.. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse.J Clin Oncol2001; 19: 3244–54
55.
BrossP.F., BeitzJ., ChenG.. Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia.Clin Cancer Res2001; 7: 1490–6
StockmeyerB., SchillerM., ReppR.. Enhanced killing of B lymphoma cells by granulocyte colony-stimulating factor-primed effector cells and Hu1D10—a humanized human leucocyte antigen DR antibody.Br J Haematol2002; 118: 959–67
58.
LundinJ., KimbyE., BjorkholmM.. Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia.Blood2002; 100: 768–73
59.
VallisK.A., ReillyR.M., ChenP.. A phase I study of 99mTc-hR3 (DiaCIM), a humanized immunoconjugate directed towards the epidermal growth factor receptor.Nucl Med Commun2002; 23: 1155–64
60.
SridharS.S., SeymourL., ShepherdF.A.Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer.Lancet Oncol2003; 4: 397–406
61.
WeltS., RitterG., WilliamsC.J.. Preliminary report of a phase I study of combination chemotherapy and humanized A33 antibody immunotherapy in patients with advanced colorectal cancer.Clin Cancer Res2003; 9: 1347–53
MarkovicS.N., SumanV.J., VukovA.M.. Phase II trial of KW2189 in patients with advanced malignant melanoma.Am J Clin Oncol2002; 25: 308–12
64.
NanusD.M., MilowskyM.I., KostakogluL.. Clinical use of monoclonal antibody HuJ591 therapy: targeting prostate specific membrane antigen.J Urol2003; 170: S84–9
65.
MurrayN., SalgiaR., FossellaF.V.Targeted molecules in small cell lung cancer.Semin Oncol2004; 31: 106–11
66.
PoseyJ.A., NgT.C., YangB.. A phase I study of anti-kinase insert domain-containing receptor antibody, IMC-1C11, in patients with liver metastases from colorectal carcinoma.Clin Cancer Res2003; 9: 1323–32
67.
WongJ.Y.C., ChuD.Z., YamauchiD.M.. A phase I radioimmunotherapy trial evaluating 90-yttrium-labelled anti-carcinoembryonic antigen (CEA) chimeric T84.66 in patients with metastatic CEA-producing malignancies.Clin Cancer Res2000; 6: 3855–63
68.
BoghaertE.R., SridharanL., ArmellinoD.C.. Antibody-targeted chemotherapy with the calicheamicin conjugate hu3S193-N-acetyl gamma calicheamicin dimethyl hydrazide targets Lewis y and eliminates Lewis y-positive human carcinoma cells and xenografts.Clin Cancer Res2004; 10: 4538–49