FrankishH.Pig organ transplantation brought one step closer.Lancet2002; 359: 137
11.
WeissR.A., MagreS., TakeuchiY.Infection hazards of xenotransplantation.J Infect2000; 40: 21–5
12.
EvansD.B., CornetteJ.C., SawyerT.K., StaplesD.J., de VauxA.E., SharmaS.K.Substrate specificity and inhibitor structure-activity relationships of recombinant human renin: implications in the in vivo evaluation of renin inhibitors.Biotechnol Appl Biochem1990; 12: 161–75
CooperD.K., GollacknerB., SachsD.H.Will the pig solve the transplantation backlog?Annu Rev Med2002; 53: 133–47
15.
SandrinM.S., VaughanH.A., DabkowskiP.L., McKenzieI.F.Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.Proc Natl Acad Sci USA1993; 90: 11391–5
16.
GaliliU., MandrellR.E., HamadehR.M., ShohetS.B., GriffissJ.M.Interaction between human natural anti-alpha-galactosyl immunoglobulin G and bacteria of the human flora.Infect Immun1988; 56: 1730–7
17.
ArtripJ.H., KwiatkowskiP., MichlerR.E.Target cell susceptibility to lysis by human natural killer cells is augmented by alpha(1,3)-galactosyltransferase and reduced by alpha(1,2)-fucosyltransferase. [erratum appears in J Biol Chem 1999; 274: 15292.]J Biol Chem1999; 274: 10717–22
18.
AzimzadehA., MeyerC., WatierH.Removal of primate xenoreactive natural antibodies by extracorporeal perfusion of pig kidneys and livers.Transpl Immunol1998; 6: 13–22
19.
TanemuraM., YinD., DiSesaV.J., GaliliU.Preventing anti-Gal response in xenograft recipients by an alpha-Gal toxin.Transplant Proc2001; 33: 699–700
20.
LeventhalJ.R., DalmassoA.P., CromwellJ.W.Prolongation of cardiac xenograft survival by depletion of complement.Transplantation1993; 55: 857–65
21.
DalmassoA.P., PlattJ.L.Prevention of complement-mediated activation of xenogeneic endothelial cells in an in vitro model of xenograft hyperacute rejection by C1 inhibitor.Transplantation1993; 56: 1171–6
22.
HeckerJ.M., LorenzR., AppiahR.C1-inhibitor for prophylaxis of xenograft rejection after pig to cynomolgus monkey kidney transplantation.Transplantation2002; 73: 688–94
23.
HuangJ., GouD., ZhenC.Protection of xenogeneic cells from human complement-mediated lysis by the expression of human DAF, CD59 and MCP.FEMS Immunol Med Microbiol2001; 31: 203–9
24.
BachF.H., RobsonS.C., WinklerH.Barriers to xenotransplantation.Nature Med1995; 1: 869–73
VangerowB., HeckerJ.M., LorenzR.C1-inhibitor for treatment of acute vascular xenograft rejection in cynomolgus recipients of h-DAF transgenic porcine kidneys.Xenotransplantation2001; 8: 266–72
27.
BachF.H., RobsonS.C., WrightonC.J., StuhlmeierK., FerranC., WinklerH.Genetic engineering of endothelial cells to ameliorate xenograft rejection.Clin Transplant1996; 10(1 pt 2): 124–7
28.
RiesbeckK., ChenD., Kemball-CookG.Expression of hirudin fusion proteins in mammalian cells: a strategy for prevention of intravascular thrombosis.Circulation1998; 98: 2744–52
29.
MiyagawaS., MurakamiH., TakahagiY.Remodeling of the major pig xenoantigen by N-acetylglucosaminyltransferase III in transgenic pig.J Biol Chem2001; 276: 39310–19
30.
SharmaA., OkabeJ., BirchP.Reduction in the level of Gal(alpha1,3)Gal in transgenic mice and pigs by the expression of an alpha(1,2)fucosyltransferase.Proc Natl Acad Sci USA1996; 93: 7190–5
31.
LaTempleD.C., GaliliU.Adult and neonatal anti-Gal response in knock-out mice for alpha1,3galactosyltransferase.Xenotransplantation1998; 5: 191–6
32.
LaiL., Kolber-SimondsD., ParkK.W.Production of alpha-1, 3-galactosyltransferase knockout pigs by nuclear transfer cloning.Science2002; 295: 1089–92
33.
ShimizuA., MeehanS.M., KozlowskiT.Acute humoral xenograft rejection: destruction of the microvascular capillary endothelium in pig-to-nonhuman primate renal grafts.Lab Invest2000; 80: 815–30
34.
HolmesB.J., RichardsA., McLaughlinM.Antibody responses in early graft rejection in pig-to-primate renal xenotransplantation.Transplant Proc2001; 33: 717–18
35.
RobsonS.C., CooperD.K., d'ApiceA.J.Disordered regulation of coagulation and platelet activation in xenotransplantation.Xenotransplantation2000; 7: 166–76
36.
TaniguchiS., NeethlingF.A., KorchaginaE.Y. et al. In vivo immunoadsorption of antipig antibodies in baboons using a specific Gal(alpha)1-3Gal column.Transplantation1996; 62: 1379–84
37.
RobsonS.C., YoungV.K., CookN.S.Thrombin inhibition in an ex vivo model of porcine heart xenograft hyperacute rejection.Transplantation1996; 61: 862–8
38.
TeranishiK., GollacknerB., BuhlerI.Depletion of anti-gal antibodies in baboons by intravenous therapy with bovine serum albumin conjugated to gal oligosaccharides.Transplantation2002; 73: 129–39
39.
SquintoS.P.Genetically modified animal organs for human transplantation.World J Surg1997; 21: 939–42
40.
IldstadS.T., SachsD.H.Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts.Nature1984; 307: 168–70
41.
AbeM., QiJ., SykesM., YangY.G.Mixed chimerism induces donor-specific T-cell tolerance across a highly disparate xenogeneic barrier.Blood2002; 99: 3823–9
42.
SablinskiT., GianelloP.R., BailinM.Pig to monkey bone marrow and kidney xenotransplantation.Surgery1997; 121: 381–91
43.
YamadaK., ShimizuA., UtsugiR.Thymic transplantation in miniature swine. II. Induction of tolerance by transplantation of composite thymokidneys to thymectomized recipients.J Immunol2000; 164: 3079–86
44.
SpeckeV., RubantS., DennerJ.Productive infection of human primary cells and cell lines with porcine endogenous retroviruses.Virology2001; 285: 177–80
45.
ParadisK., LangfordG., LongZ.Search for cross-species transmission of porcine endogenous retrovirus in patients treated with living pig tissue. The XEN 111 Study Group.Science1999; 285: 1236–41