Itch,Sneeze and Wheeze: The Genetics of Atopic Allergy

Jarvis D. , Burney P. The epidemiology of allergic disease. In: Durham S.R. , ed. ABC of Allergies. London: BMJ Books, 1998: 4–7

Shamssain M.H. , Shamsian N. Prevalence and severity of asthma, rhinitis, and atopic eczema: the North East Study. Arch Dis Child 1999; 81: 313–17

Fleming D.M. , Crombie DL. Prevalence of asthma and hay fever in England and Wales. BMJ 1987; 294: 279–83

International Study of Asthma, and Allergies in Childhood Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 1998; 351: 1225–32

Levy M. , Couriel J. , Clark R. Shared Care for Asthma. Oxford: ISIS, 1997: 5–8

Lund V.J. , Aaronsen D. , Bousquet J. International consensus report on the diagnosis and management of rhinitis. Allergy 1994; 49(S19): 1–34

Kay J. , Gawkrodger D.J. , Mortimer M.J. The prevalence of childhood atopic eczema in a general population. J Am Acad Dermatol 1994; 30: 35–9

Monticelli S. , De Monte L. , Vercelli D. Molecular regulation of IgE switching: let's walk hand in hand. Allergy 1998; 53: 6–8

Stewart A. , Haites N. , Rose P. Online medical genetic resources: a UK perspective. BMJ 2001; 322: 1037–9

[www.bshg.org.uk] (accessed May 2001)

[www.eshg.org] (accessed May 2001)

[www.archive.uwcm.ac.uk/uwcm/mg/hgmd0.html] (accessed May 2001)

Cooke R.A. , van der Veer A. Human sensitisation. J Immunol 1916; 1: 201–305

Sibbald B. Familial inheritance of asthma and allergy. In: Kay A.B. , ed. Allergy and Allergic Disease. Oxford: Blackwell Science, 1997: 1177–86

Sibbald B. Genetic basis of asthma. Semin Resp Med 1986; 7: 307–15

Edfors-Lubs ML. Allergy in 7000 twin pairs. Acta Allergol 1971; 26: 249–85

Hanson B. , McGue M. , Roitman-Johnson B. Atopic disease and immunoglobulin E in twins reared apart and together. Am J Hum Genet 1991; 48: 873–9

Weiss KM. Genetic Variation and Human Disease. Cambridge: Cambridge University Press, 1993: 92–115

Gerrard J.W. , Rao D.C. , Morton NE. A genetic study of immunoglobulin E. Am J Hum Genet 1983; 14: 61–6

Cookson WOCM , Hopkin JM. Dominant inheritance of atopic immunoglobulin-E responsiveness. Lancet 1988; i: 86–8

Hopkin JM. Genetics of atopy. In: Kay A.B. , ed. Allergy and Allergic Disease. Oxford: Blackwell Science, 1997: 1187–95

Xu J. , Levitt R.C. , Panhuysen C.I.M. Evidence for two unlinked loci regulating total serum IgE levels. Am J Hum Genet 1995; 57: 425–30

Sandfard A.J. , Pare PD. The genetics of asthma. Am J Resp Crit Care Med 2000; 161: S202–6

Cookson W.O. , Sharp P.A. , Faux J.A. , Hopkin JM. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet 1989; i: 1292–5

Cookson WOCM . Genetic aspects of atopic allergy. Allergy 1998; 53: 9–14

Thomas N.S. , Wilkinson J. , Lonjou C. Linkage analysis of markers on chromosome 11q13 with asthma and atopy in a United Kingdom population. Am J Resp Crit Care Med 2000; 162: 1268–72

Marsh D.G. , Neely J.D. , Broazeale D.R. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum IgE concentrations. Science 1994; 264: 1152–5

Meyers D.A. , Postma D.S. , Panhuysen C.L. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics 1994; 23: 464–70

Strachan T. , Read PA. Human Molecular Genetics. Oxford: BIOSIS, 1999: 283–94

Daniels S.E. , Bhattacharyya S. , James A. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996; 383: 247–50

Collaborative Study on the Genetics of Asthma (CSGA). A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 1997; 15: 389–92

Barnes P.J. , Page C. Mediators of asthma: a new series. Pulmon Pharmacol Ther 2001; 14: 1–2

Cox H.E. , Moffat M.F. , Faux J.A. Association of atopic dermatitis to the beta subunit of the high affinity immunoglobulin E receptor. Br J Dermatol 1998; 138: 182–7